A Sudden increase in floaters, small dark spots or squiggly lines that float across the vision, flashes of light in one eye or both eyes or a curtain or shadow over your vision could be a few of the warning signs prevalent before retinal detachment. If you have witnessed any of these symptoms, seek supervision from an ophthalmologist. The condition can be recognized only after a dilated eye exam.
People with the following conditions or symptoms are at an increased risk of retinal detachment.
- Family history of retinal detachment
- You have suffered certain eye injuries in the past.
- You have undergone surgeries to treat cataracts.
- You have been suffering from out-of-control diabetes.
- Extreme nearsightedness (myopia)
- Posterior vitreous detachment – a condition where the gel-like fluid in the center of the eye pulls away from the retina.
- The previous case of retinoschisis or lattice degeneration.
Stem Cell Therapy for Retinal Detachment
In a few recent researches, the iPSC cells derived from the human retina were transplanted into the sub-retinal space of monkeys with laser. The research found out that the transplanted cells integrated into the retina and formed synaptic connections with the present host bipolar cells. In the animal model of monkeys, the transplanted cells integrated into the host retinal layer and improved the electroretinogram and visually guided saccade scores were observed.
In a similar RP mouse model, sub retinal transplantation of iPSC-derived RPE spheroids delayed thinning of retinal ONL; increased pigment epithelium-derived factor levels reduced the number of apoptotic cells with a microglial infiltration in the retina.
Mesenchymal cells have also been studied extensively for their potential in the treatment of several retinal disorders. According to a recently conducted research, human dental pulp-derived MSCs on intravitreal transplantation improved the retinal function in a rat model or reversed retinal degeneration. Intravitreal injection of the umbilical cord-derived MSCs and the exosomes derived from UC-MSC into the anterior ocular chamber induced the proliferation of progenitor cells in the ciliary body. It promoted ocular regeneration and repair in the glaucoma model.
There have been several studies that analyzed the potential of MSC-derived factors and cells, engineered MSC to repair the damaged retina. Human-derived BM-MSC significantly protected RGCs and prevented retinal fiber layer thinning in a preclinical rat model of glaucoma. Injection of the stromal fraction of adipose tissue, which is enriched with pericytes, decreased vascular leakage, apoptosis and improved vision in a DR mouse model. These favorable research findings have showcased the potential of Stem Cells in improving upon the prevalent conditions of diseases like Retinal Detachment. If you have been suffering from any such conditions, Stem Cell Care India could provide some of the best alternatives for treatment. Their team of highly experienced professionals make sure that all your conditions are taken care of and attended to in the most profound manner possible. Stem Cell Care India provides treatments specifically designed to keep the unique needs of patients in mind, helping them wade through some of the unique limitations they might be suffering from. Stem Cell Care India can provide its due care whether you reside in India or abroad.