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Stem Cell Treatment for Glaucoma

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Glaucoma is a category of eye disorders that can affect the optic nerve and cause blindness. To retain stable eye pressure, the eye constantly creates a fluid called aqueous, which must drain from the eye. The most prevalent form of glaucoma is Primary Open Angle Glaucoma, in which the eye’s drainage canals become blocked and fluid builds up within the eye, allowing pressure to build up. The optic nerve, which transmits information from the eye to the brain for processing, may be affected by this strain.

Glaucoma causes peripheral (or side) vision loss, which may sound like looking into a tube or down a short tunnel at first. It’s difficult to walk without bumping into things that are off to the left, above the head, or at foot level because of this “tunnel vision” effect:

Glaucoma is a highly severe eye disease and most patients show no symptoms or warning signs when it first occurs. Glaucoma is known as the “sneak robber in sight” because of this. Glaucoma should be treated rather than healed.

Do you know about Glaucoma?

  • Glaucoma is a category of eye disorders that can affect the optic nerve and cause blindness. To retain stable eye pressure, the eye constantly creates a fluid called aqueous, which must drain from the eye.
  • Glaucoma affects more than 3 million people in the United States, and it is the leading cause of blindness among African Americans, who can begin glaucoma testing as early as age 35.
  • Glaucoma may inflict permanent harm to the optic nerve if left undetected and untreated because of issues with drainage of aqueous, a fluid generated throughout the eye.
  • The optic nerve transfers data from the eye to the brain, where it is stored.

Stem Cell Care India is the best and the most reliable stem cell treatment provider in Delhi/NCR.

  • Alcohol
  • Hepatitis B, hepatitis C
  • Non-alcoholic fatty liver disease

Since glaucoma will begin to develop without any signs, routine thorough eye tests to determine your eye pressure, optic nerve protection, thinning of the cornea, and other indicators of possible complications are the only way to protect your vision from this condition.

 

A diagnostic eye test performed by an ophthalmologist or optometrist will diagnose glaucoma. It may contain any of the following components:

An in-depth personal history of your present and previous wellbeing, followed by a discussion of all of your drugs and procedures and the immediate family’s physical wellbeing medications you’re on” can interfere with these dietary changes you are making, causing the medicines to stop working, decreasing their efficacy, or worsening their side effects (prescription and over-the-counter) can be addressed in a number of ways, including elevated blood pressure (hypertension), diabetes, alcohol, and exposure to the sun.

Your original vision, along with any recent updates, is listed below.

Glaucoma and age-related macular degeneration

Previous eye treatments, surgeries, or injuries can impact current eye treatments, surgeries, or injuries

An optical acuity examination helps you to see if you’re suffering from any eye issues. The accuracy of your reading, as well as the distance of objects, is determined by distance and close vision acuity tests

To assess whether or not your vision can be changed or corrected with normal glasses or contact lenses, you can use a system called a phoropter to put multiple lenses in front of your eyes. Your doctor will indirectly classify the propensity for glaucoma depending on the size of your eye.

A simple form of visual field research

This evaluation tests your visual vision and your field of view.

For a normal eye exam, the most common form of visual field examination is a conflict field test. Glaucoma monitoring only takes place around the outskirts of the visual field, which won’t catch patients in the early stages of the disorder. A more detailed and accurate method of visual field testing for glaucoma is listed below.

An eye test

In order to better determine the anterior section of the body, including the cornea, pupil, iris, lens, and aqueous drainage structures, an inspection using a special microscope called a slit lamp is required.

This test that is done with a mask that helps the doctor to see through the eye and inspect the retina and optic nerve also is referred to as a dilated eye examination. The specialist will prefer to use eye drops to get a clearer vision of the retina and optic nerve.

The tonometry test is a test of the fluid pressure between your pupils. This examination tests the strain between the eyes using an instrument. Intraocular pressure (IOP) can also be referred to as intraocular, as well as IOP.

Stem cells are cells that have not yet evolved into distinct cell types, but still have the capacity to differentiate into several different types of differentiated tissues.

Stem cells are usually collected from the skin, the brain, bone marrow, and the nasal mucosa in healthy adults.

Since they could potentially help shield the optic nerve from further injury and delay the development of vision loss due to glaucoma, stem cells are being studied as a potential cure for glaucoma. Ocular tissues can also be able to be replaced by stem cells if glaucoma develops in the eyes. Trabecular meshwork and optic nerve compose the drain of the eye and regulate intraocular pressure. We have no medications that will regain vision that has been damaged due to glaucoma at this time.

It is necessary to carry out some essential undertakings before stem cells can be used to treat glaucoma. In order to accurately discern stem cells into the various ocular tissues that are impaired in glaucoma, researchers need methods. in order for the stem cells to function, they must be properly inserted into the proper position inside the eye to make contacts with those regions of the brain. Since these stem cells have to remain intact for a long amount of time, and any implanted stem cells must not cause any severe side effects, they can be implanted only into patients with glaucoma.

Nonetheless, a great deal of progress has been made in the right direction, and stem cell treatment for glaucoma should be researched closely in humans. Stem cell therapy for certain degenerative diseases, including glaucoma, is available worldwide, too. There are actually no proven therapies for glaucoma, although in some cases they’ve had major adverse effects. Patients with glaucoma can only seek stem cell therapy if they have met with their particular ophthalmologist and the treatment is a part of a well-regulated clinical trial.

As well as recent, exciting advances in cutting-edge basic science research, there is a great deal of optimism and expectation for the role of stem cells in the potential treatment of glaucoma, and this is strongly supported by innovative, solid fundamental basic science studies.

How Stem Cell Therapy for Glaucoma works?

Researchers in the world of adult stem cell science, like those researching the eye, see the possibilities as thrilling. In the eye, the world’s first cellular transplantation based on iPSCs happened. Induced pluripotent stem cells (iPSCs) are stem cells that have been produced from adult cells that have been induced to differentiate.

Pluripotent stem cells are a type of adult stem cell with several possible fates. Stem cells that can proliferate and divide into various types of cells in the body, as well as replacing themselves, are special.

As well as human induced pluripotent stem cells, there are a variety of distinct pluripotent stem cell types. Adipose stem cells, which come from mature adipose tissue (body fat), are generated in adults and can be changed back to an earlier stage to produce some sort of human cell required for therapeutic purposes.

While this first transplantation occurred just ten years after iPSCs were first found, progress is currently slow to patients with vision loss who are seeking a cure. All of this being said, several successful stem cell therapies actually exist, however, they are not ready to treat glaucoma.

What to Expect from Stem Cell Treatment for Glaucoma?

Certain glaucoma patients might assume that they have little to lose by paying for an unproven stem cell therapy, particularly if they have little vision left. While it is possible to lose all of your vision or even worse, see a tumour develop on your retina, both results will occur.

Although we should take precautions to prevent fraudulent clinical testing, we can continue to engage in research with adult stem cells, particularly in the treatment of eye disease. It is just a matter of time and diligence before successful therapies are found.

VIP Treatment to Patients at Stem Cell Care India

  • The therapy sessions given to the patients at Stem Cell Care India occur in the VIP treatment room in the advanced clinic.
  • 24*7 supervision is maintained on the patients by the efficient medical team.
  • Stem Cell Care India highly recommends the patients stay for a minimum of 3 days in Hospital.

Stem Cell Care India Treatment Procedure

 

Day 1-

  • Pick up from the Airport to the Hospital
  • Interaction between Dr and Patient, to clear all their doubts at that time
  • Admission procedure
  • Clinical examination & Lab test will be done prescribed by the doctor
  • Supportive Therapy

 

Day 2-

  • Stem cell Procedure
  • Supportive therapies
  • Physiotherapy

 

Day 3-

  • Supportive Therapy
  • Physiotherapy
  • Discharging formalities
  • Drop back to the Airport

 

Note:

  • For Admission, carry the identity card (Passport/ Pan Card / Driving License)
  • Carry the hard copy of Patient reports

The following is the structure that is followed during the implantation stage:

  • Intravenous administration
  • Liberation angioplasty
  • Intrathecal (lumber puncture)
  • Intraarterial
  • Subcutaneous
  • Surgical administration for stroke
  •  Intramuscular

Many surgeries held a chance of transient or, more rarely, permanent vision loss, and healing time was normally extended. As new glaucoma therapies for intraocular pressure, laser office treatment, and minimally invasive glaucoma surgeries (MIGS) become available, we are able to give patients a range of new glaucoma drugs for treatment, laser office treatment, and surgeries (MIGS) that are easy, convenient, and successful.

In order to maintain intraocular pressure long-term, patients depend on self-administered medications to stabilise it (IOP). Advances of stem cell therapy using different techniques have recently shown promise as viable potential prevention options that can be used in combination with IOP lowering. It has been shown that several sources of endogenous stem cells have been detected in the eye, for some of which the weakened trabecular meshwork can be repaired and natural aqueous outflow activity can be restored. Neural and mesenchymal stem cells secrete growth factors which help protect the RGCs in animal models, reducing RGC loss. As stem cells are capable of replacing retinal ganglion cells (RGCs), stem cells can one day help to restore links between the eye and the brain, but the extent of this complicated repair is overwhelming. Even though stem cell therapies remain in their early stages of growth, numerous vision conditions could theoretically be handled using the latest biomaterial cell scaffolds, and amid all the difficulties that remain, there are grounds for hope that stem cells may play a role in the treatment of human glaucoma in the future.

After your procedure, you’ll need to see your doctor for follow-up exams. And you may eventually need to undergo additional procedures if your eye pressure begins to rise or other changes occur in your eye.

What causes Glaucoma?

The exact cause of Glaucoma still eludes scientists. The basic element that contributes to the damage is the blockage of passages that normally allow the fluid within your eye to drain. Because of that, fluid builds up in your eye and causes an increase in pressure on the optic nerve. The nerve fibers and blood vessels of the optic nerve are very fragile and easily damaged by this pressure, thus resulting in vision loss.

How is Glaucoma harmful to vision?

Glaucoma is harmful to vision because of the damage instilled on the optic nerve. Everything you see, that information is taken to the brain via the optic nerve. Any damage to it compromises the quality and quantity of information your brains gets, thus the loss of vision.

Will I go blind from Glaucoma?

Glaucoma is known to cause blindness but it can be prevented. If it is diagnosed at an early stage, the damage can be controlled. If you don’t treat it at the right time, you are most likely to lose peripheral vision first and then the central vision, which may result in complete blindness.

How can I tell if I have Glaucoma?

Glaucoma is infamous as ‘The Silent thief” because it steals your eyesight without any visible or loud warnings. Symptoms may not show until it is already too late. Whatever signs or symptoms you get, may vary with the type of Glaucoma.

If you have Primary open-angle Glaucoma, your first symptom might be your vision loss – which is a sign of damaged optic nerve.

If you have Acute-angle closure Glaucoma, you may have blurry vision. You might also see rings or halos around lights. You may experience pain or strain in your eye and they may also get red.

How is Glaucoma detected?

The go to test for Glaucoma is a simple and painless procedure called Tonometry. It measures the internal pressure of your eye, so the eye doctor can identify any alarming changes. Other common forms of tests used to diagnose Glaucoma include checking your eyesight and the health of the optic nerve.

How is Glaucoma treated?

Normally, Glaucoma is treated with prescription eye drops and medicines. You must take these regularly for them to be effective. In some cases, Glaucoma can be treated by therapy or surgery. To be clear, any treatment for Glaucoma does not restore eyesight, it is to prevent further vision loss and damage. That is why the sooner it is diagnosed, the better.

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