The nerve cells are the message carriers between the brain and the rest of the body, allowing us to hear, see, balance, move and feel. MS is a disease that affects the nerve cells in the brain and spinal cord. The body’s own immune system attacks the nerve cells so that they cannot function properly.
Each nerve cell is covered in a protective sheath called Myelin, which gets damaged in MS. More than half of the patients suffering from MS have progressive disease characterised by accumulating disability. More than 2 million people worldwide are affected by MS and is the most common non-traumatic disability occurring in young individuals.
There are different types of multiple sclerosis. They are
Relapsing-Remitting Multiple Sclerosis – Around 85% of people have this type of multiple sclerosis and develop the first signs of the disease in their early 20s. Attack of symptoms occurs from time to time.
Primary Progressive Multiple Sclerosis – In this type, the disease gradually gets worse over time. There is little or no recovery and there are no well-defined attacks of symptoms. About 10% of people have this type of MS
Secondary Progressive Multiple Sclerosis – Most people get secondary progressive MS after living with relapsing-remitting MS for many years. Symptoms in this type of MS begin a steady march without relapses or remissions.
Progressive Relapsing Multiple Sclerosis – It is the least common form of MS. Attacks and relapses happen very frequently but symptoms continue to get worse between relapses. About 5% of people suffer from this type.
At StemCellCareIndia, we offer promising multiple sclerosis treatment in India.
Do you know about Multiple Sclerosis?
- Multiple sclerosis is a long-term illness. Multiple sclerosis is a debilitating disease, which means it lasts a long time and has no remedy. However, it’s important to remember that MS isn’t fatal for the vast majority of people who have it. The majority of the 2.3 million people living with MS in the world have a normal life expectancy. A very few can experience complications so severe that their lives are cut short. Despite the fact that MS is a chronic disease, much of its effects can be controlled with drugs and lifestyle changes.
- MS mostly affects young adults, especially women.
According to the National Multiple Sclerosis Society, MS can be diagnosed in infants and older adults, but it is most commonly diagnosed in people between the ages of 20 and 50. (NMSS). Late-onset MS is the term used when a person is diagnosed over the age of 50. Other age-related disorders with common signs may make it more difficult for older people to get a diagnosis. Women are two to three times as likely as men to inherit MS.
- MS is a difficult disease to diagnose.
MS can be difficult to diagnose. Single tests and symptoms can not be enough to diagnose MS definitively. MS shares signs with a variety of other illnesses, making it difficult to pinpoint the cause. Multiple tests are normally required to rule out all potential causes of the symptoms, including:
- Tests on the blood
- A neurological examination
- Visual evoked potential (VEP) test magnetic resonance imaging (MRI) spinal fluid analysis optical coherence tomography (OCT)
- The signs and symptoms of MS differ.
There is a lengthy list of potential MS signs. Numbness and tingling, vision disturbances, coordination and mobility difficulties, and slurred speech are some of the symptoms. Since each person with MS has a unique experience with the disorder, there is no such thing as a “typical” symptom. The same symptoms may appear and disappear on a regular basis, or you may recover a previously missing function, such as bladder control. The unpredictability of symptoms is due to your immune system’s assault on different nerves at different times.
- Multiple sclerosis (MS) is characterised by relapses and remissions.
The majority of people who undergo MS therapy experience relapses and remissions.
Remission is described as a time over which the relapsing symptoms change. A remission will last weeks, months, or even years in some cases. However, remission does not imply that you are free of MS. MS treatments can help decrease the likelihood of new symptoms emerging, but you also have MS. Symptoms will almost certainly reappear at some stage.
- MS has a cognitive component.
MS will wreak havoc on your nerves, affecting your logical thinking and other cognitive (mental) abilities. Memory disorders and difficulty seeking the correct words to describe oneself are widespread among MS patients. Some possible cognitive consequences include:
Problem-solving abilities were harmed due to an inability to focus or pay attention.
Issues with spatial relationships (knowing where your body is in space)
Frustration, sadness, and indignation are also symptoms of cognitive disorders. There are common reactions that your doctor will track and assist you with.
- MS is an illness that goes unnoticed.
MS is known as a “invisible disorder” or “silent disease.” Since some of the symptoms of MS, such as impaired vision, visual disturbances, and chronic pain, aren’t apparent, many people with MS appear to be unaffected. Even if they don’t have any mobility problems and seem to be fine, anyone with MS may need special arrangements. MS is also known as a silent illness because it persists even while in remission. MS is often referred to as having a “silent evolution.
The reason for Multiple sclerosis is obscure. On account of MS, this invulnerable framework breakdown demolishes the greasy substance that coats (myelin) and ensures nerve filaments in the mind and spinal line. Myelin can be contrasted with the protection covering on electrical wires. At the point when the defensive myelin is harmed and nerve fiber is uncovered, the messages that movement along that nerve might be eased back or blocked. The nerve may likewise become harmed itself. It isn’t clear why MS creates in certain individuals and not others. A blend of hereditary qualities and natural variables seems, by all accounts, to be dependable.
Patients with MS may suffer from the following symptoms include
Problems with sensation, speech, swallowing, breathing and walking
Bladder and bowel issues
Tremor, Seizures, Itching
The symptoms may vary depending on which nerve cells are damaged. The symptoms may appear suddenly, and then disappear entirely as the body repairs the damaged myelin. However, when the nerve cells are damaged and begin to degenerate, they stop working all together. In the progressive stage, more nerve cells are affected, causing increasing disability.
Factors causing multiple sclerosis may include:
Geography – People in colder parts more often affected by MS than people in warmer parts.
Smoking – Tobacco increases the risk of MS
Genetics – Genes also play a role. In identical twins, if one twin has MS, the other has about 20% to 40% chances of getting MS.
Vaccines – Vaccines are not cause of MS according to research.
Epstein-Barr virus exposure – People with MS have antibodies to the EBV in their bodies. That means that they have been exposed to the virus. People ill with EBV have more risk of developing MS.
The diagnosis of MS can be a challenge for doctors as there is no test to verify its existence. But, a neurologist specialising in MS would be able to identify it. The diagnosis will include going through the patient’s medical history and symptoms. Some tests of brain and spinal cord will be done.
- MRI tests to take a closer look at the brain.
- Lumbar punctures to check the fluid that runs through the spinal canal
- Blood tests
- Electrical tests, called evoked potentials helps determine if MS has affected the nerve pathways.
Get Stem Cell Therapy for Multiple Sclerosis
Latest researches have revealed that MSCs can help restore Myelin of nervous system, improving symptoms and prolonging lives. Steroids and other disease modifying drugs cannot cover all the symptoms and are aimed to manage only specific symptoms. Again, the concern of critical side effects of drugs is also there. With MSC treatment, there is no such concern.
In StemCellCareIndia, we use the unique technology of Mesenchymal stem cells extracted from Wharton’s jelly (WJ) for treating MS. WJ-MSCs offer cost-effective and pain-free collection method that may be cryogenically stored, and are extremely favourable for tissue engineering purpose. They might help in the three prominent ways – prevent damage, repair damage and develop new medicines. The treatment will take place in multiple steps comprising of
- Qualification for the treatment: Our experts will investigate your past medical history and symptoms to assess the severity of your condition. A series of tests will be performed to understand the stage of disease. As per the test results, our experts will counsel the patient for further process of the procedure.
- Source Extraction: With guidance and approval from the physician, the source of extraction will be decided. In general, WJ-MSCs are the most potent allogenic sources available. Stem cells from a healthy person (the donor) are transferred to the patient’s body. A bone marrow donor is considered for allogenic stem cell transplantation. A scraping from the inside of the patient and his or her sibling’s cheek is tested to determine tissue type. An expert will examine to identity Human Leukocyte Antigens (HLAs). If the HLA on the donor cells are identical or similar, the transplant is more likely to be successful.
- Laboratory Processing: The extracted samples will be sent to government approved cGMP laboratory for processing. The sample manipulation will take place in a state-of-art facility in compliance with the ISO and GMP standards and using the latest technologies. The client will receive a third party certificate from internationally accredited lab for quality purpose.
- Stem Cell Implantation: Once the stem cells are ready to be implanted, the doctor will identify the most potent method of infusion based on the patient’s physical and mental well-being.
How Stem Cell Therapy for Multiple Sclerosis works?
Various kinds of cells in the body may be derived from stem cells. The blood stem cells can be dedifferentiated into a separate class, called the hematopoic stem cells. Hematopocellular stem cell transplantation (HCT) is used to treat RRMS. However, more research is required to examine the outcomes of HSCT. They offer you stem cell transplants to increase your bone marrow production. Then they get the blood to save the stem cells from it in a sample and save it for future use. You’ll then get large doses of chemotherapy as well as other highly potent drugs to diminish the immune system function. Due to the need for lengthy rest and recuperation, you will have to spend 11 days in the hospital. The stem cells are placed in your bloodstream to enable your body to develop a new, stable immune system. Some drugs, including antibiotics will be given before the immune system revives itself.
What to Expect from Stem Cell Treatment for Multiple Sclerosis?
For certain people with MS, HSCT does not function. The majority of us that have it are taking part in clinical trials, which are observational tests that determine whether a drug or medicine is safe and reliable. Five years after surgery, 69 percent of patients with RRMS who received stem cell therapy did not have a worsening in MS symptoms or new brain lesions caused by MS, according to a study of 24 people with the disease. Scientists are now searching for new ways to cure the disease using stem cells.
VIP Treatment to Patients at Stem Cell Care India
- The therapy sessions given to the patients at Stem Cell Care India occur in the VIP treatment room in the advanced clinic.
- 24*7 supervision is maintained on the patients by the efficient medical team.
- Stem Cell Care India highly recommends the patients stay for a minimum of 3 days in Hospital.
- Pick up from the Airport to the Hospital
- Interaction between Dr and Patient, to clear all their doubts at that time
- Admission procedure
- Clinical examination & Lab test will be done prescribed by the doctor
- Supportive Therapy
- Stem cell Procedure
- Supportive therapies
- Supportive Therapy
- Discharging formalities
- Drop back to the Airport
- For Admission, carry the identity card (Passport/ Pan Card / Driving License)
- Carry the hard copy of Patient reports
Implantation Of Stem Cells: The stem cell implantation can be done in the following ways.
- Intravenous administration
- Intrathecal (lumber puncture)
- Liberation angioplasty
- Surgical administration for stroke
- Why is MS therefore tough to diagnose?
The identification of MS terribly Why is MS therefore tough to diagnose?
The identification of MS terribly difficult at associate degree early stage as a result of symptoms is also very non specific and indicative of alternative diseases of the central nervous system. The first symptoms area unit terribly temporary inflicting no important injury and thus area unit most of the days unheeded simply by the folks. To boot, as such, no specific science lab check is being employed, except MRI; which may be considerably useful in identification. The entire identification is often proportional to the knowledgeable supported the standards.
2. Is MS contagious or inherited?
No, MS isn’t contagious neither it’s directly hereditary. Studies have indicated a mixed result of each genes and environmental factors on development of MS. Analysis has plain prompt that prone people could have a familial genetic contribution for MS, however, these people have to be compelled to encounter some triggering issue from the atmosphere to truly develop MS. The analysis remains afoot to pinpoint the precise location of anorexigenic sequence, its environmental cause, hindrance and higher treatment.
3. Is MS fatal?
In general MS isn’t thought of a fatal illness, however the standard of life is considerably affected in patients suffering with MS. in and of itself there’s no known full proof treatment out there to scale back the sufferings. However, several therapeutic and technological advances area unit created within the field of stem cells to search out a cure for the illness.
4. Can stem cell treatment, reverse my damage?
Yes, stem cells area unit the pristine cells of the body, which may make to several differing types of cells upon correct signaling. These cells are exploited with success to differentiate into neurons. They need been isolated from the terribly own potent sources of our body referred to as Bone Marrow and fat Tissues. They will be minimally manipulated and constituted into the body to market neuro regeneration. They need additionally known to be a good guiding system to tell apart self tissue from the non self, thereby reducing additional destruction. at associate degree early stage as a result of symptoms is also very non specific and indicative of alternative diseases of the central nervous system. The first symptoms area unit terribly temporary inflicting no important injury and thus area unit most of the days unheeded simply by the folks. To boot, as such, no specific science lab check is being employed, except MRI; which may be considerably useful in identification. The entire identification is often proportional to the knowledgeable supported the standards.
5. Is MS contagious or inherited?
No, MS isn’t contagious neither it’s directly hereditary. Studies have indicated a mixed result of each genes and environmental factors on development of MS. Analysis has plain prompt that prone people could have a familial genetic contribution for MS; however, these people have to be compelled to encounter some triggering issue from the atmosphere to truly develop MS. The analysis remains afoot to pinpoint the precise location of anorexigenic sequence, its environmental cause, hindrance and higher treatment.
The purpose of the treatment is to encourage the healing of the brain injury so as to refurbish neurological function. Consequently, numerous kinds of improvement are possible after our treatment and our former patients have experienced the following:
- Enhanced motor function
- Better-quality sensitivity
- Improved balance
- Reduced spasticity
- Heightened vision
- Diminished neuropathic pain
- Reduced tiredness
- Lowered tremor occurrence
- Amended bladder & bowel function
Mesenchymal Stem Cells (MSC) can help relieve the disease symptoms via the following mechanisms, centered on their uniquely diverse characteristics:
- MSCs can result in skeletal muscle regeneration. MSCs transplantation might enhance patient’s clinical symptoms via defective gene correction and muscle cell regeneration
- MSCs result in an apparent therapeutic benefit in disease models by their immunomodulatory effect, which is another underlying mechanism of Mesenchymal Stem Cells (MSCs) for treating Muscular Dystrophy (MD).
MSCs hold myotube generation and dystrophin expression abilities leading to muscle power augmentation in patients.
We believe that there is hope all the time and that patients deserve access to effective and safe treatments. We are independent with an in-house medical subdivision. We combine internationally recognized hospitals, pioneering treatments, unique products and amenities that are integrative and effective to impart most advantageous treatment outcomes.
33 females and 17 males were put under observation after they underwent the multiple sclerosis treatment. The average age of the patients before the multiple sclerosis treatment was around 49 years. The usual time between the treatment and the assessment/observation was about 5 months. Overall 26 patients displayed signs of improvement. 16 patients didn’t show any considerable change in their conditions, while natural illness progression was observed in s6 patients. 67.8% of the patients showed improvement in muscle strength while 76.9% showed development in the spasticity of the limbs and 56.3% demonstrated better harmonization of the limbs. 49% of the patients gained the aptitude to stand alone while 24% gained the aptitude to walk without any peripheral aid. Vision perceptiveness improved in 58% of the patients. Bowel control and bladder control function improved in 27.4% and 45.8% respectively of the whole number of patients.
Every patient gets an outsider authentication (broadly certify lab), for quality, amount of feasibility of cells.
The Staff at Stem Cell Care, India will call you following one month, two months and a half year to see the improvement of the treatment. This encourages us refine our conventions to improve further. You can likewise require some other assistance on the off chance that required.
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