Retinitis Pigmentosa (RP) is a cluster of genetic sicknesses that affect the retina’s aptitude to respond to light. This congenital degenerative disease causes a slow loss of vision, commencement with reduced night vision and loss of peripheral (side) vision. If untreated, ultimately blindness results. The retina is the layer of light-sensing cells lining the back of your eye that translates light rays into nerve impulses. The impulses are sent via the optic nerve to your brain, where they are recognized as images. With RP, cells in the retina called rods and cones die. With maximum types of RP, rods- which are chiefly in the outer regions of the retina and are accountable for our outlying and night vision, degenerate first. When the retina’s more centrally-located conduits are affected, the outcome is loss of color perception and central (reading) vision.
Stem cell treatment
The symptoms can be relieved with the use of stem cells and giving new optimism to the individuals suffering from this ailment by improving their efficacy. Patients suffering from diverse eye related disorders are treated by implanting stem cells via retrobulbar or other effective mode to obtain maximum retrieval. We are enthusiastic by the impressive prospects of stem cells in treating several diseases; hence we are continually updating our knowledge and technology to suit unique stipulations of every patient. Our chief objective has always been stoppage of disease advancement and easing the quality of life to a substantial extent in a non-surgical way. We always promise to deliver safe treatment pattern, by offering Autologous stem cells from your own Bone Marrow/Adipose Tissue. Our top priority is to offer very comprehensive, spot-on treatment pattern with the maximum retrieval. As a part of our treatment, patient’s stem cell are gotten from two sources, Adipose-derived stem cells (ASCs) and Bone marrow-derived stem cells (BMSCs). At times we might use a combination of both, contingent upon the assessment.
Do you Know about Retinitis Pigmentosa?
Retinitis pigmentosa (RP) is an inherited eye disease that results in vision loss. Night vision issues and a loss of peripheral vision are among the symptoms (side vision). Individuals can experience “tunnel vision” as their peripheral vision deteriorates. It’s doubtful that you’ll go completely blind. The onset of symptoms is usually gradual and can occur in infancy.
Retinitis pigmentosa is typically passed on by one’s ancestors. It can be caused by mutations in any of the more than 50 genes. The underlying cause is the progressive loss of rod photoreceptor cells in the back of the eye. Additionally, photoreceptor cone cells are depleted as a result of this. An examination finds black pigment crystals in the eye, and is used to make the diagnosis. Such supporting assessments include an electroretinogram, visual field testing, and genetic testing.
There is actually no solution for retinitis pigmentosa. Low vision aids, portable lighting, and orientation and mobility training are also options for dealing with the disorder. Vitamin A palmitate supplementation can be useful for incremental deterioration. Vision prosthesis could be a choice for certain people with severe illnesses. It is estimated that 1 in every 4,000 people is affected.
Patients suffering from this disorder will get the best stem cell therapy in India from Stem Cell Care India, and their symptoms have improved as a result of the stem cell treatment. The only treatment for this disease is stem cell therapy, which aims to repair the dead cells. The best team at Stem Cell Care India is dedicated to the successful management of this medical condition.
RP is an acquired issue due transformations in any of in excess of 50 qualities. These qualities convey the Guidelines for making proteins that are required inside photoreceptor cells of the retina. A portion of the changes, or transformations, inside qualities are extreme to such an extent that the quality can’t make the necessary protein, influencing the cell’s capacity. Different changes produce a protein that is poisonous to the cell. Still other changes lead to an unusual protein that doesn’t work appropriately. In every one of the three cases, the outcome is harm to the photoreceptors.
- Loss of night vision. Night blindness is when you cannot see anything in the dark.
- Gradual loss of peripheral (side) vision. This is known as “tunnel vision.”
- Loss of central vision. Some people also have problems with central vision.
- Problems with color vision.
Retinitis Pigmentosa causes sluggish loss of vision. Symptoms start with diminished night vision and later progress to loss of peripheral (side) vision — generating a “tunnel vision” effect. Some individuals might also have trouble identifying colors. The rate of vision change differs in diverse individuals contingent on the hereditary makeup of their disorder. As night vision drops, the aptitude to fine-tune to darkness becomes more challenging. You might stumble over things in the dark, find driving at dusk and night problematic and see poorly in faintly lit rooms, such as a movie theater. While your vision during the day might be totally normal, your incapability to see in dark conditions is considered “night blindness.” In some circumstances, central vision might be affected first, making detail work problematic, such as reading or threading a needle. This might be referred to as macular dystrophy, since the central area of the retina, called the macula, is affected.
Get Stem Cell Therapy for Retinitis Pigmentosa
The area of stem cell therapy for the treatment of retinal degenerative disease holds a lot of hope.
Stem cells including Umbilical Cord Blood-Derived Stem Cells (UCB-SC), Umbilical Cord Mesenchymal Stem Cells (Ucmsc), and Bone Marrow-Derived Mesenchymal Stem Cells (Bm-Msc) have the capacity to restore and improve vision from lost photoreceptors and retinal neurons.
How Stem Cell Therapy for Retinitis Pigmentosa works?
An experimental stem cell-derived treatment designed to preserve and potentially improve vision in people with retinitis pigmentosa (RP) has demonstrated a favourable safety profile in an ongoing Phase I/II clinical trial at the University of California, Irvine. Given that this study is one of the first-ever stem-cell-derived treatments for RP, this safety report is good news and a big step forward. As the experiment continues, we at the Foundation anticipate further conclusions from this study in the coming years.
The procedure entails injecting retinal progenitors, or stem cells in the process of being retinal cells, into the vitreous, a gel-like substance in the middle of the eye. Researchers conclude that the cells will produce proteins that will preserve the patient’s existing photoreceptors stable, avoiding degeneration and maintaining vision. The proteins could also be able to preserve cones that have stopped producing light but have not completely degenerated, according to the researchers.
Cones are photoreceptors that have the power to read, remember faces, and see under bright light.
What Can Retinitis Pigmentosa Patients Expect From Stem Cell Treatment?
The injection of retinal progenitors, or stem cells in the process of being retinal cells, into the vitreous, a gel-like fluid in the centre of the eye, is needed for stem cell therapy for Retinitis Pigmentosa. Researchers believe that the cells will produce proteins that will keep the patient’s existing photoreceptors stable, preventing degeneration and preserving vision. The proteins could also be able to save cones that have stopped producing light but have not completely degenerated, according to the researchers. Cones are photoreceptors charged with extending the ability to read, identify faces, and see in low-light environments. The patient’s vision improves after getting stem cell therapy from Stem Cell Care India.
VIP Treatment to Patients at Stem Cell Care India
- In the VIP recovery room in the advanced facility, the counseling sessions provided to patients at Stem Cell Care India in India occur.
- The effective care staff ensures 24*7 oversight of the patients.
- Global Stem Cell Treatment strongly advises that patients continue in the hospital for a minimum of 3 days.
Stem Cell Care India Treatment Procedure
The treatments that take place in Stem Cell Care India in Delhi, India usually last for about 3 days. The treatment protocol is safe and non-invasive. The patients can travel the next day. The following is the day-wise schedule for the patients.
- Pick up from the Airport to the Hospital
- Interaction between Dr and Patient, to clear all their doubts at that time
- Admission procedure
- Clinical examination & Lab test will be done prescribed by the doctor
- Supportive Therapy
- Stem cell Procedure
- Supportive therapies
- Supportive Therapy
- Discharging formalities
- Drop back to the Airport
- For Admission, carry the identity card (Passport/ Pan Card / Driving License)
- Carry the hard copy of Patient reports
Many people with Retinal Dystrophies and similar retinal conditions whose Unique Access has helped experience innovative therapies have seen major enhancements, including increased perceptual acuity, visual field, light intensity, and night vision, using umbilical cord derived adult stem cells.
In contrast, the progression of the disease after stem cell surgery has been much slower, resulting in years of vision preservation.
Pigmentosa Retinitis Patients who have undergone stem cell treatment typically note differences in the following areas:
- Visual acuity
- Light experience
- Eye field Night vision
- Color vision
Patients’ effects have improved as a result of stem cell therapy provided by Stem Cell Care India. Patients show substantial changes after undergoing stem cell therapy.
Implantation Of Stem Cells: The stem cell implantation can be done in the following ways.
- Intravenous administration
- Intrathecal (lumber puncture)
- Liberation angioplasty
- Surgical administration for stroke
1. Do I need to habitually examine my eyes?
Yes, it is always sensible to check your eyes frequently. Young adults between the age group 20-39 should have their eye checkups after every 3-5 years. Whereas grown-ups between the age group 40-64 should have their eye checkups after every 2-4 years. In case of senior citizens above 65 years of age, ophthalmic visit has to be once a year. Regardless of age groups, some individuals congregated under the category of high risk adults should also visit ophthalmologist once a year such as folks with diabetes, strong family history of glaucoma, persons with AIDS, etc.
2. Will working at a computer screen or sitting close to TV screen harm my eyes?
No, there is not yet any scientific indication that these instruments release rays that can be dangerous to the eyes, however long working hours can be wearisome and hence it is often useful to take episodic breaks, looking off in the distance etc.
3. Sometimes I notice dark patchy spots or floaters particularly on the white surface. Can this be the reason for me to worry?
These are the common eye complications which are signs of retinal or corneal malfunctioning. It is always desirable to visit the doctors as timely as possible.
4. I have slowly found it harder to read without glasses. Why?
The capability to focus the near objects declines with age and is referred to as presbyopia. The condition is recognized as the natural aging of the optic lens. The condition is often unalterable with conventional treatments; however, stem cell treatment for eyes can to some degree reverse the impairment naturally with complete stoppage of more progression.
5. Is my kid likely to inherit some eye problems?
Yes, some of the eye sicknesses such as glaucoma, photophobia etc. are witnessed to be directly connected up with a hereditary abnormality which can either be genetic or mutational. However, some of the common eye issues such as burns, corneal damage, etc. are associated with environmental impairment.
6.Can eyes be transplanted?
No, there are no confirmations presently to transplant the whole eyes, however portion of the eye can be replaced if an apt donor is found via eye stem cell transplant.
7. Can stem cell treatment treat my damage?
Yes, stem cells are the unspoiled cells of the body, which can give rise to several diverse kinds of cells once they get appropriate signaling. In case of eye disorders, these cells have shown amazing improvements by segregating into photoreceptor cells, rods and cones cells of the inner eyes, optic nerve cells, etc.
8. What is Retinitis Pigmentosa (RP) and how does it affect you?
Retinitis Pigmentosa is an inherited disease that causes a gradual loss of vision, including night vision and peripheral vision. Retinitis Pigmentosa occurs as the retina (photosensitive cells) of the skin is gradually disrupted. Damage to rod cells, which are responsible for vision in the dark, is followed by damage to cone cells, which are responsible for colour vision and acuity.
9. What causes Retinitis Pigmentosa (RP) in you?
Retinitis Pigmentosa is a genetic disease caused by gene defects in one or more of more than 50 genes. External factors, on the other hand, can assess and affect the rate of disease development, but they do not cause it. According to the findings, a variety of gene mutations cause the eye’s photoreceptor cells to fail, resulting in the gradual degeneration of retinal cells.
10. Will Retinitis Pigmentosa be passed on from generation to generation?
Yes, Retinitis Pigmentosa may be passed on from parents to their infants. If either parent holds the dominant gene for this condition, their child has a 1 in 2 chance of inheriting it, while if all parents bear the recessive gene for RP, their child has a 1 in 4 chance of inheriting it.
11. How does Retinitis Pigmentosa (RP) manifest itself?
Retinitis Pigmentosa symptoms can be detected in children as young as ten years old, and while the pattern and severity of this condition varies from person to person, it typically manifests as the following symptoms:
1: Nighttime visibility is decreased
2: Smudged and blurred vision
3: Inconsistent Color Differentiation
4: View of the Tunnel No.
5: Photophobia (an increased sensitivity to bright lighting, as well as irritation and pain)
12. What are the consequences of Retinitis Pigmentosa on vision?
Retinitis Pigmentosa has three main effects on vision:
1: Causes nighttime blindness.
2: Tunnel vision is a condition that occurs while a person has tunnel vision.
3: The difference between hue and acuity is unclear.
Every patient gets an outsider authentication (broadly certify lab), for quality, amount of feasibility of cells.
The Staff at Stem Cell Care, India will call you following one month, two months and a half year to see the improvement of the treatment. This encourages us refine our conventions to improve further. You can likewise require some other assistance on the off chance that required.