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Optic Nerve Hypoplasia Stem Cell Treatment in Delhi, India

Optic nerve hypoplasia (ONH) befalls from the underdevelopment of the optic nerve, the sole purpose of which is to carry neuronal transmission from the retina in the eye to the brain. Septo-optic dysplasia (SOD), also recognized as de Morsier syndrome, is a subtype of ONH and ascends from the underdevelopment of the optic nerve, pituitary gland dysfunction and deficiency of the septum pellucid, which is a mid line region of the brain. SOD ascends from shortcomings during the embryological development of babies and studies show that ONH might be connected to some gene defects as well as embryo exposure to infections. Along with this the deficiency of vision which is a characteristic symptom of ONH, SOD also elicits other symptoms such as pituitary deficiency, autistic behaviors, epileptic seizures, etc. Optic Nerve Hypoplasia stem cell is the treatment for such ailments.

Few conventional treatment choices are available for patients detected with ONH-SOD, it typically concentrates on assisting the patients to cope up with their incapacity. However, none of them are essentially treating the loss of optic nerve function. Optic nerve hypoplasia stem cell treatment in India has the aptitude to rejuvenate nerve cells in the optic nerve, permitting ONH-SOD patients to gain some vision.

Do you Know about Optic Nerve Hypoplasia?

  • Optic nerve hypoplasia (ONH) develops in 70 percent to 80 percent of patients and is normally the first presentation symptom, preceded by hormonal anomalies. Some eye disorders, such as nystagmus and microphthalmia, can also be present.

Septo-optic dysplasia (SOD), also known as de Morsier Syndrome, is characterised by optic nerve hypoplasia (ONH), pituitary hypoplasia, and midbrain defects such as lack of septum pellucidum and corpus collasum agenesis. Patients with this disorder have received the best treatment from Stem Cell Care India, and their conditions have changed as a result of the stem cell treatment.

  • The only treatment for this disease is stem cell therapy, which aims to repair the dead cells. The best team at Stem Cell Care India is dedicated to the successful management of this medical condition.

· Neurological disability is widespread, ranging from global retardation to focal deficits including epilepsy or hemiparesis. Traumatic optic neuropathy, optic neuritis, and ischemic optic neuropathy are also common causes of vision loss, although they are seldom linked with other conditions.

Optic Nerve Hypoplasia Symptoms

ONH is present at birth, but certain symptoms may not occur until puberty or even adolescence. Most babies with ONH have involuntary, erratic eye movements (nystagmus) and/or mild to significant vision disability in one or both eyes. Even if the optic nerves do not mature after birth, vision still improves modestly in early childhood. When examined by a physician using an ophthalmologist, the optic disc in one or both eyes is thinner than average due to underdevelopment of the optic nerves.

The “blind spot,” the structure where nerve fibres from the retina connect before exiting the back of the eye to form the optic nerve, is known as the optic disc. The optic chiasm and optic tracts are created where the optic nerves converge at the base of the hypothalamus.

The hypothalamus coordinates the function of the pituitary gland by controlling the gland’s release of certain hormones. Multiple hormones are formed in the pituitary gland and released directly into the bloodstream through a tiny mechanism underneath the hypothalamus.

It is located immediately under the optic nerves and is connected to the hypothalamus by a small stalk of nerve fibres and blood vessels. In certain people with ONH, the hypothalamus does not interact well with the pituitary gland, causing the pituitary gland to produce or release insufficient levels of such hormones into the bloodstream. Stem Cell Care India offers patients in Delhi stem cell treatment for Optic Nerve Hypoplasia.

Optic Nerve Hypoplasia Diagnosis

The involvement of the small/pale optic nerve during a dilated eye test is usually enough to diagnose ONH. It’s impossible to determine visual acuity potential depending on the appearance of the optic nerve. The bulk of cases of ONH have no apparent cause. There are no known ethnic or socioeconomic reasons for ONH, and there is no known connection between ONH and pesticide exposure. ONH has been linked to maternal phenytoin, quinine, and LSD use, as well as foetal alcohol syndrome. In Delhi, the best clinics for stem cell therapy can be located. The best stem cell treatment provider in India is Stem Cell Care India.

Most cases of ONH have no clearly identifiable cause. There are no known racial or socioeconomic factors in the development of ONH, nor is there a known association with exposure to pesticides. ONH has been associated with maternal ingestion of phenytoin, quinine, and LSD, as well as with fetal alcohol syndrome.

Stem Cell Processing Method

Umbilical cord collection and preliminary testing.

It is a common practice in India for mothers to voluntarily donate the umbilical cord blood from the birth of their kids. Every mom who enters a hospital in India to give birth is spontaneously tested for all main sicknesses. Comprehensive family histories are also taken from each mother before donation. Only females who have been fully screened and found to be totally healthy are allowed to donate their umbilical cord and umbilical cord blood.

Second Round of Testing

The second step in the screening procedure happens in the laboratory once the collected samples have been verified affirmatively for communicable ailments; it is then transported to our laboratories and officially becomes the property. From this phase, it is mandatory for each and every sample to be processed and provided to the patient. The gathered samples are then run through a second round of testing and while following donor’s prerequisite also carries out testing for cytomegalovirus, micro-organisms (aerobic bacteria, anaerobic bacteria, fungi, etc.), survival rate, stem cell surface indicators and stem cell biological characteristics (colony forming aptitude, differential capability) in each step to safeguard the highest quality to its cell products.


The stem cells derived from each umbilical cord are sowed into a flask filled with culture medium. This medium does not have any animal products (such as fetal calf serum) but it is heightened with cell growth factors. The flasks are positioned in a sterilized, temperature and humidity controlled incubator. The stem cell treatment for optic nerve hypoplasia is considered best suited. The stem cells are lengthened in the culture medium. Once the culturing is done, the culture mediums are splashed away and are harvested.


The cell products are then cryo-preserved and stored at a consistent -196 degree Celsius temperature with an automatic supply of liquid nitrogen using the exceedingly advanced Thermogenesis Bio Archive system. This technology permits for integrated control rate of freezing that absolutely avoids unexpected drops in temperature. Our cryo-preservation storage equipment is also fortified with 24h real-time control system and in any situation of power-failure or other emergency; a redundant fail-safe power supply guarantees that normal operation is implemented. Our vacuum protection system can uphold appropriate temperature for up to 20 days without supplement of liquid nitrogen. The Optic nerve hypoplasia Hospital ensures efficient storage of the stem cells for further use.

Packing and Transport

All consignments of stem cells undergo final testing. During this procedure, they are tested for both quantity as well as quality. Once the stem cells are reckoned safe, each unit is positioned into either a sterile vial or a sterile IV bag for future transplantation. All merchandises are separately cataloged and traced while in transit. Our cell transplants come to pass two to three days a week. All of our cells are processed as per the requirement. Our cell products are verified, treated and kept fresh, giving us the highest stem cell sustainability count and the maximum effectiveness. We provide the best optic nerve hypoplasia stem cell treatment in Delhi with our network of experienced hospitals.

Get Stem Cell Therapy for Optic Nerve Hypoplasia

Detailed research on the effectiveness of stem cell transplantation has been carried out using a range of cell sources, including umbilical cord blood stem cells (UC-BSC), umbilical cord blood-derived mesenchymal stem cells (UCB-MSC), and bone marrow-derived mesenchymal stem cells (BM-DMSC) (BM-MSC). Stem cell therapy by Stem Cell Care India results in nerve tissue regeneration, improved blood flow, and a significant reduction in inflammation. A respected treatment specialist including Stem Cell Care India provides the best stem cell therapy in India. It is the most effective cure for Optic Nerve Hypoplasia, as shown by the child’s improvement.

How Stem Cell Therapy for Optic Nerve Hypoplasia works?

The detailed stem cell therapy protocols for Optic Nerve Hypoplasia (ONH) and Septo-Optic Dysplasia (SOD) for Optic Nerve Hypoplasia (ONH) and Septo-Optic Dysplasia (SOD) for Optic Nerve Hypoplasia (ONH) and Septo-Optic Dysplasia (SOD) for Optic Nerve Hypoplasia (ONH) and Septo-Optic Dysplasi

They also address the disease’s root cause by promoting the regeneration of the optic nerve and other weakened brain structures. We believe that our comprehensive ONH-SOD treatment approach provides our patients with the best chance to improve their vision and overall quality of life.

What to Expect from Stem Cell Treatment for Optic Nerve Hypoplasia?

The aim of stem cell therapy at Stem Cell Care India is to restore neurological function in the area of brain/spinal cord lesion, so various types of recovery are possible after our treatment, and our previous patients have undergone the following:

Visual acuity improved; light perception improved; visual field expanded; brighter night vision improved; nystagmus reduced; strabismus improved; hormonal disorders improved Autism symptoms have become worse.

VIP Treatment to Patients at Stem Cell Care India

  • In the VIP recovery room in the advanced facility, the counseling sessions provided to patients at Stem Cell Care India occur.
  • The effective care staff ensures 24*7 oversight of the patients.
  • Global Stem Cell Treatment strongly advises that patients continue in the hospital for a minimum of 3 days.

Stem Cell Care India Treatment Procedure

The stem cell therapy for Optic Nerve Hypoplasia takes place in Stem Cell Care India, usually takes place for about 3 days. The treatment protocol is safe and non-invasive. The patients can travel the next day. The following is the day-wise schedule for the patients. Stem cell therapy in Delhi, India is offered by the best and the most reliable stem cell care hospitals.

Day 1-

  • Pick up from the Airport to the Hospital
  • Interaction between Dr and Patient, to clear all their doubts at that time
  • Admission procedure
  • Clinical examination & Lab test will be done prescribed by the doctor
  • Supportive Therapy

Day 2-

  • Stem cell Procedure
  • Supportive therapies
  • Physiotherapy

Day 3-

  • Supportive Therapy
  • Physiotherapy
  • Discharging formalities
  • Drop back to the Airport


  • For Admission, carry the identity card (Passport/ Pan Card / Driving License)
  • Carry the hard copy of Patient reports

Possible Improvement


Patients’ effects have improved as a result of stem cell therapy provided by Stem Cell Care India. The aim of stem cell treatment for Optic Nerve Hypoplasia is to restore neuronal activity in the brain and spinal cord that had been compromised previously. Patients show significant changes after receiving stem cell therapy. Optical acuity, visual field, light sensitivity, night vision, strabismus, and nystagmus are all signs of optic nerve diseases, and treatments involving MSCs have proven to be successful. In adults with advanced diseases, stem cell treatment has resulted in a noticeable slowing in vision loss.

Patients with optic nerve hypoplasia (ONH) and septo-optic dysplasia (de Morsier Syndrome) who receive stem cell treatment usually notice differences in the following areas:

  • Acuity of vision
  • Perception of light
  • Range of vision
  • Seeing in the dark
  • Color interpretation
  • Nystagmus is a condition in which a person’s

Frequently Asked Questions


An MRI scan is indicated for any child who has hypoplasia of the optic nerve. An endocrinologist’s evaluation should be required for any patients under the age of five years.



On the whole, ONH is a stable, non-progressive condition that does not worsen. Nystagmus can subside as vision improves.



On the medical or surgical fronts, there is no treatment for ONH. However, occlusion of the better-seeing eye will help the other eye see better. Poor vision therapists may help children with serious vision loss in both eyes get the help they need early on. The use of stem cells as a treatment for ONH has not proved to be successful.


Is it possible to reverse the effects of optic nerve hypoplasia?

Pediatricians, ophthalmologists, neurologists, endocrinologists, and other primary care professionals form part of the treatment team. Hormone replacement therapy is used to treat hormone disorders caused by endocrinologists. Low vision patients may seek assistance, but vision deficiencies in ONH and SOD patients are usually not treatable.

Implantation Of Stem Cells: The stem cell implantation can be done in the following ways.

  • Intravenous administration
  • Intrathecal (lumber puncture)
  • Intramuscular
  • Intraarterial
  • Subcutaneous
  • Liberation angioplasty
  • Surgical administration for stroke

The purpose of our stem cell treatment is to reinstate neurological function in the brain/spinal cord lesion region, thus, plethora of improvements are suitable and can be opted after the treatment, the previous patients have shown signs of following:

  • Improved visual insight
  • Improved light perception
  • Enlarged visual field
  • Perkier night vision
  • Abridged nystagmus
  • Enriched strabismus
  • Better-quality hormonal deficiencies
  • Reduced autistic symptoms

It is vital and imperative to remember that as for any medical treatment, improvements cannot be promised. Please contact us for more info, regarding the possible improvements for any specific case. If you are looking for assistance with Optic nerve hypoplasia stem cell treatment in India, trust StemCellCareIndia, to provide you the best treatment.

Every patient gets an outsider authentication (broadly certify lab), for quality, amount of feasibility of cells.

The Staff at Stem Cell Care, India will call you following one month, two months and a half year to see the improvement of the treatment. This encourages us refine our conventions to improve further. You can likewise require some other assistance on the off chance that required.

Ask Your Query

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If you have any queries related to stem cell treatments, let us know via phone or email. Our healthcare experts will be happy to provide you with an effective treatment solution.


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