Can Diabetes be Successfully Treated with Stem Cells?

Diabetes is a devastating ailment that affects millions of individuals globally. The major forms of the disease are type 1 and type 2 diabetes. In type 1 diabetes, the body’s immune system perversely abolishes the insulin-producing beta cells (b-cells) of the pancreas. Type 2 diabetes, the more common form, is categorized both by insulin resistance, a condition in which numerous tissues in the body no longer respond appropriately to insulin action and by consequent progressive deterioration in b-cell function to the point that the cells can no longer create sufficient additional insulin to overcome the insulin resistance. Researchers are keenly exploring cell replacement therapy as a prospective strategy to cure type 1 diabetes, since patients with this disease have lost all or approximately all b-cell function. However, if a safe and cost-effective means for replenishing b-cells were developed, such a treatment approach could also be advantageous for the bigger population with type 2 diabetes. One of the major challenges of cell replacement therapy is the present inadequate supply of b-cells from human organ donors. This article emphasizes on stem cells as prospective sources for springing new b-cells.

What is diabetes?

Diabetes ascends from the body’s incapability to regulate the concentration of sugar (glucose) in the blood. Blood glucose concentration is modulated by insulin, a hormone produced by pancreatic b-cells and released into the bloodstream to maintain homeostasis. In healthy folks, b-cells counteract sharp upsurges in blood glucose, such as those instigated by a meal, by releasing a preliminary “spike” of insulin within a couple of minutes of the glucose challenge. This acute release is then followed by a more sustained release that may last for several hours, depending on the persistence of the elevated blood glucose concentration. The insulin release steadily tapers as the body’s steady-state glucose concentration is reinvented. While postprandial insulin release is stirred by factors except blood glucose, the blood sugar concentration is the chief driver. When the b-cells fail to produce sufficient insulin to meet regulatory requirements, however, the blood glucose concentration rises. This elevated concentration imposes a metabolic encumbrance on several body systems, dramatically raising the risk of premature cardiovascular disease, stroke and kidney failure. Furthermore, the jeopardy for certain diabetes-related complications upsurges even at blood glucose concentrations underneath the threshold for diagnosing diabetes.

Categories of diabetes

As noted earlier, there are diverse forms of diabetes. Type 1 diabetes results when an individual’s immune system erroneously attacks and destroys the b-cells. This kind of diabetes was once referred to as “juvenile-onset diabetes,” since it typically starts in childhood. Type 1 diabetes accounts for 5–10% of diabetes circumstances, and folks with type 1 diabetes depend on everyday insulin administration to survive. By contrast, type 2 diabetes is a metabolic ailment that results from a drop in b-cell function pooled with insulin resistance, or the incapability to use insulin effectually in peripheral tissues such as the liver, muscles and fat. Onset is related with genetic aspects and with obesity and type 2 diabetes unreasonably affects certain minority groups. 3 Unlike type 1 diabetes, type 2 is chiefly avoidable.

Can diabetes be treated with stem cells?

In the recent year, clinical examinations about stem cells treatment have been progressed dramatically, to configure numerous diverse outcomes in treating degenerative disorders. These treatments are recognized to be the most pleasing as they directly work on the root cause of the problem, reversing the conditions to minimalize their relative after effects, such as progression, pain and symptomatic management of the ailment.

Conventional medicines for countless degenerative disorders, such as orthopedic conditions as well as metabolic disorders are either anti-inflammatory steroidal medicines or operation; so as to manage pain and other locomotary problems. However, long-term usage of steroidal medicines can be hazardously allied with multiple organ failure; while surgery has never been a viable option, because of the cost involved as well as risk related with the same. In this regard, countless scientists and medical specialists are supporting stem cells treatment as minimally invasive as well as risk-free option to use body’s natural aptitude to heal. Stem cells are recognized to be the mother cells of the body, with the capability to reproduce infinite times and transmuted into cells of diverse tissue origin. They are the leading cells, accountable for formatting a whole cellular makeup of the human body, during fetal development inside the mother’s womb. In fact, a small fraction of these mighty cells is being stowed in the form of a reserved share in each adult mature organ and can be used to maintain cell number intact, in case of impairment because of normal deterioration of the body. However, some of the exterior as well as internal factors are responsible for deranging the cell number, as in number of cell demise is more than its production; recognized to be as the diseased condition. In such disorders, a reserved share of cell is never adequate, demanding for supplementary supply of stem cells; in which stem cells treatment can be advantageous.

Technological advances have permitted easy access to these stem cells isolated from bone marrow and adipose tissue; autologous stem cells sources. These stem cells are supplemented under controlled conditions and can be imbued back at the place of injury. In case of neurodegenerative ailments, stem cells are vaccinated straight in the cerebrospinal fluid, while in case of orthopedic ailments they are added in the joints. Targeted delivery of stem cells is approved to be advantageous owing to limited likelihood of them getting lost in the vascular system. Once imbued in the body, these stem cells create a picture-perfect homing environment, by regulating immune cells, secreting diverse growth factors and stimulating resident stem cells to multiply and burgeon further. The regulatory effects can emphasize clinical outcome, because of more tissue specific differentiation of stem cells and reverse detrimental effect due to autoimmunity and disease progression. Thus, stem cells treatment has been found to be effective in:

  • Speedy retrieval and swift healing
  • Pain management, omitting the requirement for steroidal medicines
  • Improving functionality, including flexibility, range of motion and quality of life
  • Decreasing risk for progressive impairment

Numerous research and clinical studies have so far proven that stem cells exhibit the infinite aptitude to treat potential damaging ailments, which wouldn’t have been treated via conventional treatment.

diabetes treatment

How Can Stem Cells Act as a Blessing for Diabetic Patients?

Diabetes has been one of those ailments which cause many other sicknesses within the same individual. A diabetic individual might already have to face many other maladies only because of this disease. One of the simple reasons for this is that the individual’s immunity lowers enormously. It makes the diseased individual weak and inept to cure little injuries even bruises. In this ailment, the specific individual fails to extract sugar molecules form the blood and they get defecated out of the body with urine which causes feebleness in an individual. Furthermore, the body fails to yield chemical named insulin which controls the absorption of glucose form the blood. But now diabetes stem cell treatment in India ensures a perpetual cure from this disease at StemCellCareIndia.

Stem cell therapy for diabetes has unbolted new doors and horizons for all diabetic folks all around the globe. These are the source of the treatment of diabetes in this method. Let us see how this method aids in getting cure from this disease: It encompasses the inoculation of stem cells into the body where impairment is occurring. As these cells have the aptitude to convert into any other kind of the cell, they cure the ailment by developing and transmuting into the essential cell type. These new and healthy cells replace the impaired cells. These cells are effectual in overhauling the cells because they have the talent to divide without any constraint and take on the same persona as the impaired cells except they are new and fresh.

diabetes treatment

How Can Mesenchymal Stem Cells Help to Cure Diabetes?

Not many individuals are sentient that there is a diabetes epidemic that is now impacting health care systems across the globe, particularly India. Even fewer folks are aware that we have the solution to this epidemic i.e. mesenchymal diabetes stem cell treatment in India. Many of us think of diabetes as that ailment where you have to take insulin shots. In reality, there is much more to it than that. Impediments of diabetes include amplified risks of heart disease, stroke, blindness, kidney infection, amputations, dental syndromes and others. The health costs to treat these conditions are also cosmic.

The diabetes epidemic displays no sign of decelerating despite new advances in diabetes drugs. It is already consuming huge portions of the national health budgets of monetarily weaker countries like India.Nobody accurately comprehends that this epidemic has the power to annihilate the medical infrastructures of some economically sturdier, developed nations over the next 15 years. We think that if we can just get our diabetics to take their pills, then diet and workout, all will be well. While this is perhaps true for the average diabetic, the fact is maximum diabetics will not follow any diet. In such a scenario, it is superlative to seek expert assistance regarding diabetes stem cell treatment in India at StemCellCareIndia. Stem cell treatment using mesenchymal stem cells are successfully assisting diabetic people across the nation.As progressively more folks realize the advantages of stem cells, the more lives will be saved.

Stem Cells Can Cure the Most Deadly Disease of All viz. Diabetes!

diabetes treatment

Diabetic stem cell research is breathing optimism into the pursuit for a cure, particularly for type 1 diabetes. Stem cell therapy for diabetes patient that reverses type 1 diabetes and then relieves type 2 diabetics as well might seem like a reverie. But approximately every day, there is some electrifying new thing researchers are reporting about this new type of cell. That is because all across the globe, scientists are reviewing them. But the controversy over the source of stem cells has dwarfed the subject. If you wish to know more about these cells, you can refer StemCellCareIndia.

What These Cells Are

Diabetic stem cell treatment for all of us may be far-flung, but it is a worthy idea to comprehend those cells themselves. As you know, every separate cell in your body has a specific job. Muscle cells pump blood in your heart and make you capable to walk. Nerve cells carry information to other body organs. A muscle cell cannot perform the function of a nerve cell. So, your cells cannot do anything other than what they are consigned to do. But, this was not always so. You began as a single cell that separated into many. At about five days old you were an embryo, and you were made up of some very distinctive cells. Over the next nine months those unspecialized cells would become tissues, organs, skin, hair and everything that makes up your body now.