Amyotrophic Lateral Sclerosis (ALS), often called Lou Gehrig’s disease after the renowned baseball player’s struggle with this disease and later died of the same in 1941 grabbed national attention. It is an incurable, progressive degenerative neurological disorder. The nerve cells of the brain and spinal cord that controls the voluntary muscle movement gradually decline for no apparent reasons. The muscles waste away, leading to paralysis and death of the person in 2-5 years’ time. The only neurons affected are the lower motor nerve cells which control a wide range of things like movement of limbs, swallowing, and even breathing. There are ALS treatment centers in India, who specialize in providing the best treatment to cure the disease.
Motor neurons run from brain to the spinal cord and from the spinal cord to the muscles throughout the body. The progressive degeneration of the motor neurons eventually leads to their death. When motor neurons die, the ability of the brain to start and control muscle movement is lost. This also affects a person’s ability to speak, eat, move and breathe. In ALS, the motor neurons that provide voluntary movements and muscle control are affected. Research has revealed a wealth of new scientific understanding about the physiology of this disease. Stem cell treatment for Amyotrophic Lateral Sclerosis has emerged as an effective treatment option for ALS.
Do you Know about Amyotrophic Lateral Sclerosis?
ALS (Amyotrophic lateral sclerosis), which is characterised by muscle weakness and the appearance of ALS can also be caused by mutations in the TSC1 gene This disease also involves nerve cells in the brain and spinal cord, with the possible progression affecting the motor neurons.
Neurons provide the urge or prompt to activate the desired muscle in ALS. Walking, for example, is not a complex signal to do so there is no action of the voluntary muscles necessary. This is deadly if not treated. It is four or five years on average, but in rare circumstances, it can be as long as seven years. but due to the recent advancements of medical science, a breakthrough in care for ALS occurred because stem cell therapies are not as safe as they used to be ( regeneration of affected portion of the brain ).
ALS can be inherited in 5 to ten% cases, at the same time as the others don’t have any known cause. Other viable reasons are being investigated. Gene mutation or other genetic causes are underneath investigation, howeversome different instances showcase no genetic link.
The beginning of ALS may be so blurred which causes the symptoms to be frequently ignored. The earliest symptoms may include:
- Slurred and nasal speech
- Difficulty chewing or swallowing
- Muscle weakness affecting an arm or a leg
- Spasms, cramps, or stiffness of muscles
Depending on the muscles in the body that are damaged first the early symptoms of ALS surface. Symptoms initially affect one of the legs and patients experience difficulty in running or walking, or they experience sudden stumbling or tripping more often. The signs of this disease first appear on the hands or arms and they experience difficulty in pursuing simple tasks requiring manual agility such as writing, turning a key in a lock and other. Some patients notice speech problems as well.
ALS affects the upper motor neurons, which are in the brain, and the lower motor neurons, which are in the spinal cord and brainstem. Upper motor neuron degeneration generally causes spasticity (tightness in a muscle), while the lower motor neuron degeneration causes muscle weakness, muscle atrophy (shrinkage of muscles) and twitching. These can occur in combination to ALS, as upper and lower motor neurons can be lost at the same time.
Though it usually strikes people in their late middle age, ALS can affect the people of any age. It is characterized by persistent weakness or spasticity in an arm or leg. The problem originated in the muscles incorporating controlling speech or swallowing. People facing such issues cannot ignore the problem and must see a doctor.
To diagnose ALS, a neurologist will administer electromyogram (EMG) for the detection of nerve damage. Electromyogram (EMG)
- Nerve conduction study
- Magnetic resonance imaging (MRI)
- Blood and urine tests
- Spinal tap (lumbar puncture)
- Muscle biopsy
Latest researches have revealed that MSCs can help restore Myelin of nervous system, improving symptoms and prolonging lives. Steroids and other disease modifying drugs cannot cover all the symptoms and are aimed to manage only specific symptoms. Again, the concern of critical side effects of drugs is also there. With MSC treatment, there is no such concern.
In StemCellCareIndia, we use the unique technology of Mesenchymal stem cells extracted from Wharton’s jelly (WJ) for treating MS. WJ-MSCs offer cost-effective and pain-free collection method that may be cryogenic ally stored, and are extremely favorable for tissue engineering purpose. They might help in the three prominent ways – prevent damage, repair damage and develop new medicines. The treatment will take place in multiple steps comprising of
Qualification for stem cell treatment for ALS in Delhi: Our experts will investigate your past medical history and symptoms to assess the severity of your condition. A series of tests will be performed to understand the stage of disease. As per the test results, our experts will counsel the patient for further process of the procedure.
Source Extraction: With guidance and approval from the physician, the source of extraction will be decided. In general, WJ-MSCs are the most potent allogenic sources available. Stem cells from a healthy person (the donor) are transferred to the patient’s body. A bone marrow donor is considered for allogenic stem cell transplantation. A scraping from the inside of the patient and his or her sibling’s cheek is tested to determine tissue type. An expert will examine to identity Human Leukocyte Antigens (HLAs). If the HLA on the donor cells are identical or similar, the transplant is more likely to be successful.
Laboratory Processing: The extracted samples will be sent to government approved cGMP laboratory for processing. The sample manipulation will take place in a state-of- art facility in compliance with the ISO and GMP standards and using the latest technologies. The client will receive a third party certificate from internationally accredited lab for quality purpose.
Stem Cell Treatment for Amyotrophic Lateral Sclerosis Implantation: Once the stem cells are ready to be implanted, the doctor will identify the most potent method of infusion based on the patient’s physical and mental well-being. The risk of treatment by Adult Autologous Stem Cell is minimal and limited to the normal risks of surgical intervention. Because the used cells are patient’s own, there is no risk of rejection or side effects. The treatment by own steam cells can significantly slow down the ALS symptoms and prolong patient’s life.
Stem Cell Treatment for ALS in India Aftercare: The patients will be asked to visit the doctors for some tests to analyze the improvement. Suggestive rehabilitation programs may include behavior and emotional development, communication and social interaction, self-regulation, cognitive and adaptive skills.
What to Expect from Stem Cell Treatment for Amyotrophic Lateral Sclerosis?
The treatments currently available assist to some degree with day-to-day life and academics, but they don’t cure the root cause of developmental delays. There is a significant need for improving standard treatment approaches at this time. Stem Cell therapy is now an attractive recovery choice for people with Amyotrophic Lateral Sclerosis . This latest method of therapy for Neurodevelopmental conditions is just emerging. The use of cell therapy in the early stages of behavioural issues will assist with the development of undesirable behaviour patterns. Decreasing hyperactivity, increasing sitting endurance, and reducing behaviour that’s combative and defiant are a few of the ways you can help your child succeed. The result of this is that his learning ability and gripping force are increased. His listening skills have also improved. He has a greater understanding of interpersonal relationships and develops an awareness of himself. Cell therapy is possible through the use of stem cells from many sources. Trophic factors are also released into the ecosystem that helps to minimise destruction, and differentiation occurs, into several forms of nervous system cells such as oligodendrocytes, glial cells, and other nervous system cells.
- Prevention of neuronal cell death
- New blood vessels are developed
- The growth of cell numbers and functionality
- To discover new functions, the brain has to develop new neural maps.
In these instances, the injured tissue is mended and regenerated, returning the damaged region to its previous function level, and it translates into therapeutic changes. In the long run, this helps make life better for the whole community. Autologous bone marrow, MNCs (i.e. your own bone marrow, or your own cells) do not show any side effects and are not rejected by the immune system. Even, they originate from the same patient, making them ethically clean.
VIP Treatment to Patients at Stem Cell Care India
- The therapy sessions given to the patients at Stem Cell Care India occur in the VIP treatment room in the advanced clinic.
- 24*7 supervision is maintained on the patients by the efficient medical team.
- Stem Cell Care India highly recommends the patients stay for a minimum of 3 days in Hospital.
- Pick up from the Airport to the Hospital
- Interaction between Dr and Patient, to clear all their doubts at that time
- Admission procedure
- Clinical examination & Lab test will be done prescribed by the doctor
- Supportive Therapy
- Stem cell Procedure
- Supportive therapies
- Supportive Therapy
- Discharging formalities
- Drop back to the Airport
- For Admission, carry the identity card (Passport/ Pan Card / Driving License)
- Carry the hard copy of Patient reports
We are so special because we were each born in a different way. Some people are born with great health for the remainder of their life, and others may suffer from neuromuscular disorders, and the rest of us may suffer from degenerative diseases. The concept of stem cell therapy has been used to cure a variety of conditions ranging from minor to life-threatening. Using stem cells, this therapy choice aids in the treatment of a variety of illnesses and non-life threatening problems. Such stem cells can be used in a variety of places and may be used to cure more than 80 different diseases, including degenerative diseases and neuromuscular disorders.
The degenerative ailment is a condition caused by problems such as bone wear and tear, skin, cartilage, tissue, or any weight, cell, or organ degeneration. This can be used for a variety of reasons, but one of the most common is the ageing process and growing up. The diseases can have a gradual and insidious onset, but once contracted, they can be long-term, permanent, and excruciating. Many of these illnesses have the potential to damage every organ in the body. Stroke, diabetes, osteoarthritis, congestive heart failure, chronic renal failure, Alzheimer’s disease, myocardial infarction, and Parkinson’s disease are examples of degenerative diseases that can be treated with stem cell therapy.
There has been a rapid development in stem cell therapies in India, and it is not being too optimistic to expect that in India and around the world, stem cell therapies will one day be able to replace the expensive, time-consuming, and often infective conventional therapies for stuff like curing a variety of chronic disorders and acute issues. In other words, stem cells may be referred to as a “force of nature” that is responsible for wound healing, organ formation, and the recovery of a variety of problems in the patient. This isn’t all; adding up the rejuvenating results can be referred to as the “real” fountain of youth. When it comes to reaping the full benefits of stem cell therapy, however, there is no shortage of options available in this area.
The stem cell implantation can be done in the following ways.
- Intravenous administration
- Surgical administration for stroke
- Liberation angioplasty
- Intrathecal (lumber puncture)
- What Is ALS?
ALS is the sickness poignant in which the brain cells popularly referred to as neurons connecting the brain with alternative elements of the body, act as messengers to transmit signals from the brain to muscles. This procedure is eminent since it permits the voluntary movements of the body. Thanks to some external or internal factors, these cells die or degenerate thereby losing the power to transmit signals to muscles. This cause the muscles to be weak resulting in palsy.
- What Causes ALS?
Although, ALS has been terribly current worldwide, scientists still conduct group action to grasp the precise cause and mechanism for ALS. There are to this point numerous studies conducted to analyze completely different sides that can be clubbed with ALS. Though studies square measure correlating the sickness of many genetic variations, there’s nonetheless way to be understood.
- Is ALS connected with setting?
Clinical studies to this point haven’t found definitive environmental factors which can be joined with ALS, except some generalized studies relating it to the potential exposure of bound chemicals like lead or mercury.
- Is ALS equally common in each the genders?
ALS, that has been induced, thanks to some environmental factors, is generally determined to be common in men than in ladies. But it has conjointly been according recently that the distinction is decreasing over the time. At the same time, familial ALS i.e. ALS related to the genetic variations is equally common in each genders.
- Is ALS associated with age?
ALS is usually age related; most of the individuals resolve that they’re suffering with ALS after they are between 55-75 years mature.
- How long do individuals with ALS live?
Most of the individuals with ALS have been determined to be live for three to five years when the symptoms develop. Though the precise lifetime of a person affected with ALS is associated with age.
- Can ALS be familial?
It has been determined that nearly about 5-10% of the whole ALS cases square measure familial ALS i.e. they’re largely caused thanks by the defect within the factor that is usually referred to as “SOD1”
- What is a efferent neuron disease?
ALS falls underneath a bunch of conditions referred to as efferent neuron sickness. In ALS, muscles concerned within the voluntary movements of each higher and lower body square measure is affected. On a median, ALS usually accounts for about eighty fifth of the efferent neuron diseases.
The purpose of the Stem cell treatment for ALS in India is to encourage the healing of the brain injury so as to restore neurological function. Thus, a number of varieties of improvement possible after the stem cell treatment and our previous patients have experienced the following:
- Enhanced motor function
- Amended balance
- Enhanced coordination
- Diminished fatigue
- Augmented muscle tone and strength
- Lowered tremor occurrence
- Better speech and swallowing
- Decelerated general disease progression
Stella from Brazil Came India for Stem Cell Treatment for ALS
Stella, a 48-year-old patient from the Brazil, got stem cell treatment for ALS and continues to see progresses in her health state. Stella received regenerative treatment, which included inoculations via IV and lumbar puncture, physiotherapy, and occupational therapy. Following the treatment, this 48-year-old ALS patient reports that she saw more than a few improvements to her condition. Getting up on her own feet, Stella observes more power in her legs as well as in the joints. Also, she can now sit up with the shoulder and back straight. In her interview, Stella shared her feelings that she has made a correct decision coming here to go through stem cell treatment. She is also enormously enthusiastic to see even more improvements in the future.
Jossie from Australia Came India for Stem Cell Treatment for ALS
Jossie, 34 from Australia was detected with ALS. She tried to learn as much as she could about the ailment and prospective treatment alternatives. Eventually, she learns about Stem Cell Care India. She reached out and spoke with one of SCCI’s patient representatives. After more than a few calls, she decided to go through stem cell treatment here. Jossie felt more drained and exhausted before starting her treatment. Via the blend of treatments she got at SCCI, she made momentous progress towards retrieval. On top of stem cell therapy, Jossie underwent an amalgamation of occupational therapy, physical therapy, and hydrotherapy. These treatments were tailor-made specifically to engage her body in a way that matches her stem cell treatment. In addition to the treatment she got, Jossie was comprehensively impressed with the admirable quality of care she got from the team of SCCI. She also appreciated the environment and quality of the facilities that she saw here.
Noah Woods, 47 year old American Came India for Stem Cell Treatment of Amyotrophic Lateral Sclerosis
Noah Woods, a 47-year-old American patient was spotted with Amyotrophic Lateral Sclerosis (ALS). In a quest for a treatment that would support her, Noah’s friend discovered Stem Cell Treatment at Stem Cell Care India. After an in-depth research, Noah became more assertive in this treatment plan available in India. As a part of her personalized treatment plan, she received stem cell injections via IV and lumbar puncture, which according to her is the most crucial method in the procedure; and also an extensive Rehabilitation program, including occupational therapy, physiotherapy, etc. She stated “the staff here was brilliant and rapidly replied to all the questions I had. The fact that the doctors in charge are so much experienced and veteran people involved in stem cell therapy internationally made me feel tremendously privileged and that I couldn’t be in better hands. Within his first 10 days of my Stem Cell treatment for ALS, I began showing signs of advancement.” She showed an enhanced aptitude to speak and swallow. She was also markedly stronger than when she first arrived for the stem cell treatment.
Julie From United States Came India for Stem Cell Treatment of Amyotrophic Lateral Sclerosis
Julie was diagnosed with ALS while in the United States. She tried her level best to find a treatment that would suit her maximum, but the exploration proved fruitless. After eyeing at a few options online, she decided that Stem Cell Care India’s stem cell treatment protocol in India was very broad and was precisely what she was eyeing for. Thanks to the stem cell treatment, Julie is now able to stand without any difficulty, swallow better and her hands have amended too, as equated to before getting the treatment. She was enthralled by the care she had gotten during her treatment here in India. She also claimed that the facilities were extremely hygienic and the food was great too.
Every patient receives certificate which is a third party certificate from nationally accredited laboratory that is an evidence of quality, quantity and viability of cells.
The Staff at Stem Cell Care India will call you following one month, two months and a half year to see the improvement of the treatment. This causes us refine our conventions to improve further. You can likewise require some other assistance on the off chance that required.
Pari Shukla From Ghaziabad Came for Tuberous Sclerosis
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