Retinopathy is a disease of small retinal blood vessels which further leads to several complications and left untreated retinopathy can lead to significant vision impairment. Therefore, it’s essential to undertake regular eye exams to ensure that unfavorable changes are recognized as early as possible and proper care could be taken, and medical help could be taken from them. Some of the issues untreated retinopathy can cause are.
If left untreated, the growth of scar tissue propelled by the abnormal blood vessels associated with diabetic retinopathy can impact the retina and stretch it away from the back of the eye. This can cause spots floating in the eye and flashes of light or vision loss.
- Vitreous Hemorrhage
Blood vessels under pressure might bleed into the clear jelly-like substance that fills the center of the eye; if the amount Is small, only a small amount of blind spots would be visible; in severe cases, blood can fill the vitreous cavity and completely block your vision. The blood often clears from the eye and does to cause any permanent vision loss; unless your retina is damaged, your vision would likely return to its previous clarity.
New blood vessels can grow on the front of your eyes and interfere with the flow of fluid in and around the eyeballs leading to an increase in pressure in the eyes. This pressure can further damage the nerves that transmit images from the eyes to the brain and cause glaucoma.
Stem Cell Therapy for retinopathy
According to recent research, a population of retinal cells localized to the pigmented ciliary margin can differentiate into different retinal cells, such as rod photoreceptors, bipolar cells and Muller cells. These group of cells since have been denoted as late-stage neuronal progenitors or pigmented ciliary epithelial cells. Neural progenitor Stem Cells are essential to retinal development as a retina is a specialized appendage of the Nervous system.
The multipotent characteristics of the progenitor cells are essential for appropriately developing the intricate details of the eye and retina. For this main reason, many researchers have considered that there could be regenerative potential in the damaged or degenerated retina through the transplantation or activation of stem cells. However, initial attempts at transplanting neural and retinal stem cells into damaged retina proved to be unsuccessful. But after, research conducted by Maclaren et al., noted that the mammalian retina can incorporate rod photoreceptors precursors derived from post-natal day 1 Retina of mice into the outer nuclear layer. According to what was observed, the cells differentiated, formed functional synapses, and improved vision in mouse models of degenerative retinal disease.
Others have observed that the transplantation of the embryonic stem cell-derived neural progenitors leads to the enhanced survival of host retinal cells such as photoreceptors and improved preservation of visual function in the MND mouse model of neuronal ceroid lipofuscinoses. It has been suggested that the secretion of growth factors could mediate this enhanced survival of host cells. For Stem Cell Therapy in India, contact Stem Cell Care India and ensure that all your treatment is conducted as smoothly as possible; their highly trained professionals and experts devise a holistic approach including all possible treatments for the present ailment. Whether you reside in India or anywhere around the world, you can communicate your needs to our expert doctors and ensure all your needs are catered to.