How Effective Is Stem Cell Therapy For Stroke Patients?

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Stroke patients may benefit from stem cell treatment. Stem cells are an exciting new therapeutic option that has been shown safe and beneficial in many peer-reviewed research. It prevents additional harm to the body and brain after a stroke by rebuilding damaged brain cells and controlling the immune system. Stem cell treatment for stroke survivors is a useful alternative treatment option because of these features.

What exactly is a stroke?

A stroke happens when blood flow to the brain is interrupted, depriving the brain of oxygen for a short period of time.

Every year, approximately 795,000 individuals in the United States suffer from strokes, which may strike at any age. Until recently, there was little that could be done to prevent brain damage from a stroke if it was not detected early and treated within hours of its onset. Recent research and clinical trials using stem cells on actual stroke patients, on the other hand, have shown incredible outcomes.

What is the cause of a stroke?

A stroke may result from a lack of blood flow to the brain (ischemic) or from a haemorrhage (bleeding within the brain).

What is an Ischemic Stroke, and how does it happen?

Ischemic strokes, on the other hand, are produced by tiny blockages in the blood artery. These are often plaque fragments or blood clots. Annually, ischemic strokes account for approximately 87 percent of all strokes. In either instance, cutting off blood supply to the brain causes brain cells to die within minutes, potentially resulting in long-term brain damage and neurological problems. To dissolve the blood clot, conventional therapies such as tissue plasminogen activators (tPA) were utilised till recently. They are generally useless in avoiding long-term impairment if not given within hours after a stroke.

What is stem cell treatment and how does it work?

Stem cell therapy is a non-invasive procedure for replacing damaged cells in the body. Mesenchymal stem cells may be injected locally or systemically to target particular areas, depending on the requirements of the patient.

Because of their anti-inflammatory and immunoregulatory properties, stem cells may be able to assist stroke victims. Stroke may be treated safely using stem cell therapy. If given early enough, stem cell therapy may help in stroke recovery. (1)

Can stem cells assist those who have had a stroke?

Stem cells are regenerative and anti-inflammatory by nature, and they seek out damaged tissue in the body. As a result, Stanford University School of Medicine used stem cells in clinical studies to treat stroke patients of various ages, ranging from 6 months to 3 years following their stroke. The study included 18 people, with an average age of 61, and utilised direct brain stem cell transplantation.

The stem cells used in the research were taken from a donor’s bone marrow. All of the individuals exhibited indications of better motor function after just a few months. The Fugl-Meyer Assessment, a stroke-specific impairment test, revealed an average gain of 11.4 points in the patients, and the effects lasted for years following therapy, as tracked by the institution. This study made significant progress in demonstrating that stem cells may successfully treat stroke symptoms years after the stroke has occurred, and that they can be used at any age.

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Stem Cell Therapy For Stroke

Where Can I Get Stem Cell Therapy For Stroke?

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How Can Stem Cells Act As A Boon For Stroke Patients?

Adult stem cells therapy is used to cure stroke, Alzheimer’s disease, motor neuron disease, Parkinson’s disease, etc. The cells that are used are from our own body as other cells might be forbidden by our body. They can be considered as our body’s reparation kit. Since our body overhauls itself continuously, when we are struggling with some degenerative ailments, our cells can no longer create at a speed that they should be. A healthy body necessitates an optimal level of immune system. Consequently, if your immune system is feeble, your body will not be able to guard itself from ailments. Stem cells therapy is said to be advantageous to cure stroke. For those who do not know, a stroke is a medical complaint where blood does not reach the brain because of the manifestation of clots. If not cured instantaneously, it can result in severe medical disorders. Some of the signs of stroke are cited below:

  • A sudden feebleness on one side of the body or numbness in arms, legs, etc.
  • The incapability to understand words and thoughts and helplessness to speak
  • Severe headaches with no distinct reason
  • One or both eyes experience loss or fading vision
  • Imbalance in motor movements

What is stroke stem cell treatment?

Stroke stem cell treatment encompasses the procedures and techniques that use stem cells to treat the stroke patients. Stem Cell Care India is one of the most distinguished organizations that offer medical help and backing for the treatment of stroke via stem cell therapy. Stem cell therapy for stroke patients can be tremendously effective as a form of treatment. The brain impairment suffered by a patient during a stroke can be very damaging to him. Stem cell therapy can help improve the performance of his brain and other succeeding motor actions, thoughts and speaking. Stroke stem cell therapy, accompanied by medicine, can help the patient enormously with recovery and restoration. Stem cell therapy helps replace a person’s compromised and exhausted cells with new, functioning cells. When these stem cells are mined from the patient himself, there is no risk of his body rebuffing the cells. The new stem cells make their way to the impaired tissues and repair and replace the deceased or lost cells, therefore, helping the patient to recuperate from the destruction of brain cells befallen during a stroke. Stem cell stroke treatment can discharge cytokines and trophic factors. These are tremendously useful in halting further impairment of brain cells and improving blood supply to the brain. As strokes are caused because of blood not being able to reach the patient’s brain owing to clots, generation of new blood vessels and augmented supply of blood can be tremendously advantageous for the brain and other organs. The cytokines and trophic factors also help in revival of neurons in the affected zones.

Therefore, the extensive recent meta-analysis ratifies that stem cell therapies offer impressive promise, through statistically noteworthy improvement in both sensory and also motor outcomes, in patients struggling with stroke or spinal cord injury.  Stem cell therapy is unquestionably the finest available therapeutic solution for numerous degenerative illnesses that had no treatment alternatives using conventional medicine; but scientists will be able to control the variables stated here within couple of years. Research on how stem cells can be used for restoring impaired brain tissues is enticing lots of attention, as this can turn around infirmity of individuals and can be a defining moment for stroke treatment. Stem cell therapy research is not just concentrating on replacing impaired brain tissues but it targets at averting impairment at the very first phase only. Millions of individuals die as a consequence of stroke and the survivors generally lose their aptitude to move and even perform everyday chores by themselves.

New hope with stem cell treatment

Until now, the probabilities of enduring a stroke and further stroke treatment depends how rapidly a patient gets medical attention. However, proffering medical support within minutes is not always possible, so patients are administered with customary treatment alternatives. Rigorous physical therapy is administered to help recuperate lost functionalities of the body, but still there is no comprehensive stroke treatment option for restoring the cells of the brain, which expired owing to the stroke. However, with stem cell therapy this problem can get a perpetual solution, as this type of therapy aims to replace impaired cells and put healthy cells in their place, so that the affected portion can function routinely, or at least the impairment done is diminished to improve condition of the patient. The process for stem cell treatment for stroke patients is very rapid and simple. It is also not very dangerous and is a brilliant option for treatment and retrieval for stroke patients. If you are wondering where can I get stem cell therapy for stroke, the best place is Stem Cell Care India.

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How Effective Is Stem Cell Therapy for Stroke

How Effective Is Stem Cell Therapy for Stroke

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When the fresh oxygenated blood supply to the brain gets suddenly disrupted due to a ruptured blood vessel or blood clots, the brain cells die leading to a stroke. Some of the symptoms of a stroke are sudden numbness or weakness on one side of the body, trouble speaking, dizziness, loss of limb coordination, disturbed vision in one or both eyes, loss of balance while walking, and severe headache. If an individual exhibits such symptoms, cell therapy for stroke is the most suitable treatment to stop further dire consequences and to regain brain plasticity.

Causes

  • Obesity
  • Smoking
  • High blood pressure and cholesterol
  • Diabetes
  • Heart ailments, such as blood clot and irregular heart rhythm that can lead to stroke
  • Family history of stroke
  • A previous history of stroke or mini-stroke

After-effect of stroke

Although stroke caused due to the damaged brain, it affects the entire body. This may result in a complete paralysis on one side of the body, also known as hemiplegia. The effect of stroke causes problems with cognition skill, attention, learning disability, and memory loss. Stroke patients face problems understanding or forming speech that leads to emotional issues. They also experience depression, numbness, strange sensations of pain which is worse in areas like the hands and feet.

Treatment

Treatment for stroke depend on factors such as its type and severity. The sooner is the individual receives help after a stroke, there is a better chance for a quick recovery. The three main types of stroke are:

Ischemic (Clots)

An Ischemic stroke occurs when the blood vessels that supply blood to the brain get obstructed due to clots or the fatty deposits lining the vessel walls (atherosclerosis).

Hemorrhagic (Haemorrhage)

Hemorrhagic stroke is triggered by blood vessels that rupture and haemorrhage resulting in blood accumulation and compression of the surrounding brain tissue. The two types of hemorrhagic strokes are subarachnoid and intracerebral haemorrhage.

Transient Ischemic Attack (TIA)

A Transient Ischemic Attack is a temporary blockage of the blood flow that does not cause permanent damage, but at times is a signal for a major stroke ahead.

The treatment comprises of cell therapy and post-stroke rehabilitation therapies. Cell treatment is aimed at treating the underlying symptoms by replacing the damaged tissue caused by bleeding and blood clots. The main goal of stroke treatment with stem cells is to restore the normal blood flow to the brain. Stem cells extracted from the marrow-derived from the patient’s hip bone has the potential to replace the damaged neurons and to self-renew indefinitely for years. With the properties of division and regeneration, they help to repair the cells and tissue of the brain and blood vessels.

Process

Cell therapy for stroke is accomplished by using stem cells derived from the bone marrow of the patient. The surgical procedure followed by the neurosurgeons involves: The extraction of 80 to 120 ml of marrow tissue from the hip bone of the patient using an aspiration needle. The extracted marrow tissue undergoes a density gradient centrifugation procedure to separate the required stem cells from the unwanted tissue. These stem cells subjected to a quality check at the laboratory. These stem cells are intrathecally injected into the spinal area of the patient from where they travel to the damaged areas of the brain with the help of cerebrospinal fluid. They reach the tissue site and activate their repairing process to replace the dead or damaged cells. During the healing process, they repair the damaged blood vessels and restore the constant flow of blood supply to the brain. Post-stroke, cell treatment, rehabilitation therapies help in overcoming the disabilities. Depending on the severity of the damage, individuals are advised speech therapy, physiotherapy, and diet counselling to help them regain their lost abilities. Cell therapy for stroke is the most suitable treatment to stop further dire consequences and to regain brain plasticity.

New hope with stem cell treatment

Until now the chances of surviving a stroke and further Stroke Treatment depends how fast a patient gets medical attention. However, providing medical aid within minutes is not always possible, so patients are administered with traditional treatment options. Rigorous physical therapy is administered to help regain lost functionalities of the body, but still there is no complete Stroke Treatment option for reinstating the cells of the brain, which died because of the stroke. However, with Stem Cell Therapy this problem can get a permanent solution, as this kind of therapy intends to replace damaged cells and put healthy cells in their place, so that the affected part can function normally, or at least the damage done is minimized to improve condition of the patient. Stem Cell Therapy research also aims at making such treatment fully safe and effective for patients so researchers always keep an eye on the effects or even side effects that occur after injecting stem cells into a patient’s body.

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Does Stem Cell Therapy Work For Stroke Patients?

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How Does Stem Cell Therapy Work For Stroke Patients?

A stroke ensues when the blood supply to one or more portions of the brain is abridged or totally choked. The obstruction might be provisional or perpetual and it can be instigated in two diverse ways:

  • In ischaemic stroke a blood clot hinders the supply of blood to the brain
  • In hemorrhagic stroke a blood vessel spurts and bleeds into the brain

All portions of the brain need to have a good blood supply to work appropriately. When the movement of blood is restricted or clogged, important nutrients and oxygen cannot reach the cells in the brain and they are impaired or they die. The effects on the body depend on which portion of the brain is impaired and how long the obstruction remains. A stroke can affect movement, speech, thought progressions and memory. It can cause paralysis in one or more portions of the body, or loss of control of physical functions. Around 40% of people affected by stroke will have perpetual symptoms that lead to them requiring special care. Various folks’ symptoms improve considerably after a stroke, but only around 10% of patients recover completely. Anybody of any age can have a stroke, but there are some vital risk factors. The probability of having a stroke upsurges with age, for instance. Certain ethnic groups are more in jeopardy and a family history of stroke upsurges the chance that you might be affected. There are also risk elements that we might reduce through lifestyle modifications like making certain any high blood pressure is cured, eating a healthy diet low in fat and salt, ending smoking and staying physically energetic.

What causes a stroke?

A stoke can be instigated by a loss of blood supply to the brain (ischemic) or a hemorrhage (bleeding within the brain).

Stroke can be treated with stem cells

Stroke is the third principal cause of demise in the U.S. and the leading reason of serious, long-standing adult disability. Every year, over 700,000 people have a stroke; 75% of these are first attacks. Knowing the cautionary signs and acting rapidly are our preeminent defenses against stroke. After a stroke, millions of brain neurons expire within minutes. While the deceased cells can’t be reinstated, some tissue around the deceased zone remains active but non-functioning. While stem cells are still being used in clinical trials, there is proof that joined with clot busting and mechanical thrombectomy, therapy augments retrieval. Stem cells injected into distant arteries or veins travel to the location of a stroke in the brain to fuel the repair procedure. The optimum time for introducing stem cells appears to be between 36 and 72 hours after the stroke. Investigation has found that stem cells target the region with chemicals that save and revitalize that tissue. The optimal time for introducing stem cells seems to be between 36 and 72 hours after the stroke. Although the study involved a trivial number of patients, outcomes were promising enough to plan on a bigger study. Strokes impair big regions of the brain. Although therapies and stem cell treatments might aid to reestablish patients’ motor function and repair portions of the brain, severely impaired areas might be enduringly devastated.

How does stem cell therapy work?

Stem cell therapy is a non-invasive treatment that targets to replace impaired cells within the body. Mesenchymal stem cells can be deployed systemically through IV or injected locally to target particular sites, contingent on patient requirements. Stem cells might have the capability to help stroke patients via their anti-inflammatory and immunoregulatory competences.  Stem cell therapy is a safe treatment for stroke.  Stem cell treatment might also help in stroke retrieval if administered early.

Can stem cells help stroke victims?

If you ask does stem cell therapy work for stroke patients, stem cells have a naturally regenerative and anti-inflammatory effect, looking out for impaired tissue in the body. For this reason, Stanford University School of Medicine turned to stem cells for clinical trials in curing stroke victims of diverse ages, anywhere from 6 months to 3 years after their stroke had befallen. The trial encompassed 18 individuals, an average age of 61, and used stem cell transplant therapy straight to the brain.  The stem cells in the study are derived from donor bone marrow. Within months, all partakers exhibited signs of enhanced motor function. The patients displayed an average upsurge in 11.4 points on the Fugl-Meyer Assessment, a stroke-specific damage test and the outcomes held for years after treatment as supervised by the university. This trial made marvelous strides in proving that stem cells could effectually treat stroke symptoms years after a patient’s stroke incidence, and could also be effective at any age. Intravenous injection of allogeneic mesenchymal stem cells can both be a safe and effective treatment choice for post-stroke long-term retrieval.

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