Learn How And What Type Of Stem Cells Are Used For Treating Parkinson’s Disease
Before we delve into the phases and treatment for Parkinson’s disease, let us first go into what this disease is about. Parkinson’s disease is a degenerative ailment of the central nervous system. It was first defined in 1817 by James Parkinson, a British physician who printed an article that he named “the shaking palsy.” It is categorized by inflexibility of muscles within broad or narrow regions of the body. It is epitomized by quivering and the whole loss of voluntary movements. Other symptoms of Parkinson’s consist of augmented salivation, sweating and seborrheic secretion. Parkinson’s disease is a chronic progressive nature, which continues for a protracted period of time, which means that the symptoms deteriorate with time. It is not transmissible. Lots of researchers now believe that the ailment stems from a mixture of genetic vulnerability and exposure to one or more environmental aspects that elicit the disease. Viruses are another probable environmental reason of Parkinson’s. Parkinson’s disease is a gradually progressive malady that affects movement, muscle control and stability. It primarily affects individuals over 40 but can appear in younger individuals. The ailment has numerous phases, which aid the doctor to decide what treatment for Parkinsons will be carried out. The numerous stages are:
- Stage One – Symptoms only on single side of the body.
- Stage Two – Symptoms on both sides of the body. No worsening of one’s stability.
- Stage three – Damage of balance. Mild to moderate sickness. Physically independent.
- Stage Four – Severely incapacitated, but still can walk or stand unassisted.
- Stage five – In a wheelchair or in bed unless you get assistance.
Tremors, muscle inflexibility and other symptoms of Parkinson’s disease (PD) are triggered by the demise of dopamine-producing neurons in the brain. Dopamine-producing neurons in the brain are affected, but the ‘substantia nigra’ is the main brain area where neurons are misplaced. Individuals affected by PD often develop uncharacteristic protein clumps in their brain named Lewy bodies. These clusters are made of a protein named alpha-synuclein. Presently, there is no treatment for Parkinson’s disease but at times medicines or surgery can offer intense respite of its symptoms. Parkinson’s disease can be a problematic ailment to see in a once healthy and active loved one. It is vital to know and notice initial the symptoms of Parkinsons. As with maximum illnesses, the early you can know it, the more effective the treatment for Parkinson’s will be. New research scrutinizes the potential of stem cell therapy in the replacement of impaired neurons in Parkinson’s disease. The authors say that stem cells could offer superior treatment, perhaps using diverse types of cells to treat diverse symptoms of Parkinson’s.
Stem cells for Parkinson’s disease – Is this the answer?
The thought of losing your mind is indeed very upsetting, however new investigation in the arena of stem cells Parkinson’s disease appears very encouraging and might well prove to be the solution for people with sicknesses such as dementia, Lou Gehrig’s or Parkinson’s disease. Research has now specified that by using adult stem cell therapy, there is no requisite to use the controversial embryonic stem cells therapy method. This novel therapy offers the potential for these disorders to be considerably improved and there appears to be pristine hope on the skyline for those with family or friends that are affected. In Parkinson’s disease (PD), cells that make the chemical messenger dopamine degrade and expire. Introducing new dopamine cells into the brain might help substitute what is lost in PD and decrease its symptoms. Such a treatment also could decrease medicine side-effects. Long-standing usage of the most commonly suggested PD medication (levodopa) and progressing ailment can result in dyskinesia or unrestrained, involuntary movements. Stem cells can be used in the lab to produce several other categories of cells, including dopamine cells. Induced pluripotent stem cells (iPS cells) are derived from adult cells (generally from skin or blood) and can be influenced to act like stem cells.
What type of stem cells are used to treat Parkinson’s disease?
If you ask what type of stem cells are used to treat Parkinson’s disease, the answer would be Human Mesenchymal Stem Cells (hMSCs). These are non-hematopoietic and multipotent self-renewing cells ascending effortlessly from adult bone marrow, adipose tissue, umbilical cord blood, placenta, etc. In the previous few years, these cells have arisen as a promising methodology to regenerative medicine because of their remarkable proliferative potential and extensive availability in the body. The present treatment choices accessible for most neurological disorders, including PD, only provide temporary symptomatic respite but do not avert the disease from progressing. Consequently, the development of cell-replacement therapies could offer extensive advantages for PD patients.