Osteoarthritis occurs when the cartilage that cushions the ends of the bones in your joints deteriorates due to age or any other factor. The cartilage is a firm and slippery tissue that enables frictionless movement. With increased wearing down of such tissues, there occurs a situation where the bones start to grind upon the connecting bones and cause pain, tenderness, and swelling.
The impact of osteoarthritis is greater than the wearing down of a single cartilage; it impacts the whole joint, impacting the quality of life, ease of movement, and ability to be agile and flexible. Over its course of progression, osteoarthritis also causes degeneration of the connective tissues that hold the joint together and attach the muscle to bone. In certain cases, it also causes muscle inflammation as well as inflammation of the joint lining.
Who is more prone to get the disease?
A certain class of individuals who suffer from other underlying health issues and the presence of certain other health conditions are more prone to contract the disease.
People at an older age are more susceptible to getting osteoarthritis as the ability of the body to regenerate scarred tissue decreases over time. People above the age bracket of 50 are more prone to experience osteoarthritis.
According to the medical data collated over the years based on the medical records, women are more likely to develop osteoporosis with age than men.
Being overweight can lead to osteoarthritis in several ways. First, the increased weight adds stress to weight-bearing joints, such as hips and knees. Also, the fat tissue present in the body also produces proteins that cause harmful inflammation in and around your joints.
- Repeated stress on the joint
If your profession involves running around or increased and repetitive stress upon your joints, the joints might eventually develop osteoarthritis.
Genetics and family history with the disease also play an integral role in the development of osteoarthritis.
- Bone Deformities
Certain people are born with malformed joints and cartilage, which increase the chances of osteoarthritis in the long run.
- Certain metabolic-related issues
These issues would involve situations where the body has too much iron, known as hemochromatosis or diabetes.
All these conditions and symptoms are manageable with the right kind of medication, treatments, and therapy sessions. However, the most concerning issue of the whole disease is that the pain and stiffness increase with the progression of the disease.
Stem Cell Therapy for Osteoarthritis
Stem Cell therapies are of great interest in regenerative medicine due to their potential to regenerate new cartilage and immune regulatory solid capacity. However, positive results in the pre-clinical and clinical trials have demonstrated that MSC-based therapies can cause long-term defects of not down with critical care and discretion.
This has been elucidated because, as of now, there exists an inadequate understanding of MSC’ regarding their physiological properties and cellular formations in vitro and in Vivo.
Another reason to pay much attention and care to the treatment remains because many factors have influenced the therapeutic efficacy of the MSC in pre-clinical and clinical studies. These include cell culture conditions, cell density, the time and location of MSC transplantation, and the pre-treatment of MSCs by LLLT or inflammatory cytokines. Despite the fact that the challenges, MSC-based therapies are becoming a promising approach to regenerative medicines and the treatment of osteoarthritis. For osteoarthritis treatment with Stem Cell therapy, Medicare insurance does not settle any kind of insurance claims since government regulatory institutions have not recognized these therapies, but Stem Cell Care India can perform these therapies at competitive prices contact today.