A severe blockage in the arteries of the lower extremities, which further reduces blood flow, causes a severe form of peripheral arterial disease. The disease is less common than claudication. This claudication is caused by atherosclerosis, the hardening and narrowing of the arteries over time due to the buildup of fatty deposits called plaque.

CLI is a chronic condition that results in severe pain in the feet and toes while resting. The complication for such diseases can include sores and wounds that are hard to heal; left untreated, the complication of the disease can rise to such as level that it would require amputation of limbs or other parts.

Diagnosis

Since it’s a disease that can be recovered from if recognized early, here are a few tests that are necessary from the medical perspective to locate blockages and channel out their cause.

• Auscultation– in this test presence of a bruit or a whooshing sound in the arteries of the legs are listened to. These help in figuring out tampered blood flow in the limbs.
• Ankle Brachial Index – the systolic blood pressure in the arm is divided by the systolic pressure at the ankle; any differences are then managed accordingly.
• Doppler ultrasound – a type of ultra sound that can measure the velocity and direction of the blood flow through the vessels.
• CT Angiography: Use of an advanced X-ray procedure that uses a computer to generate 3D images of the area suffering from issues.
• Magnetic Resonance Angiography– The patient is exposed to radiofrequency waves in a strong magnetic field. The energy that is then released is measured by a computer and used to construct two and three-dimensional images of the blood vessels.
• Angiogram– An x-ray taken using contrast dyes that are used to study the blood vessels and their conditions.

Treatment options

• Angioplasty: A tiny balloon is inserted through a puncture in the groin then the balloon is inflated using saline solution to help the artery open up and improve blood flow.
• Stents – Metal mesh tubes that provide scaffolding are implanted into the place, collapsing due to damage. This is generally done after angioplasty has already been conducted upon the patient.
• Laser atherectomy – A small bot of plaque that gets accumulated within the blood arteries and is vaporized by the tip of a laser probe.
• Directional atherectomy – a catheter with a rotating cutting blade is inserted to physically remove the plaque from the artery, opening the flow channel and rehabilitating the blood flow.

Stem Cell treatment for the condition

Stem Cell Therapy for limb ischemia involves injecting cultured cells into the damaged area to help them rehabilitate faster and without any issues. The procedure is not very painful, but the level of pain depends upon the type of procedure, and the severity of the disease one is suffering from. A practicable form of the procedure is resisted from execution due to the following challenges. Ischemic diseases using life and autologous stem cells.

However, according to the current research, the ESC niche is derived from an inappropriate tissue, provides a high potential to generate an array of cellular populations alongside their low immunology, will make this lineage a new source of LI regeneration; using this method, and designing translational studies and then measuring the direct regenerative effects of ESC’s on the failed limbs remains to be one of the main approaches that can be sued. For stem cell therapy in India, contact stem cell care India for the most accurate and beneficial treatment. Their team of ace doctors can ensure a safe treatment without any hassles; contact them today for a full-fledged treatment.