A Hyderabad-born scientist, Fyyaz Siddiqui, who is now working in Canada and his research found that stem cells have the best potential in treating neuroinflammation and it may result in several neurodegenerative disorders entailing blindness. This is for the very first time that stem cells have been used in controlling neuroinflammation and neurotoxicity. Without any doubt, neuroinflammation is a serious disease that can cause cognitive impairment and vision loss too.
This Hyderabad-born scientist is the associate director of the neuro research wing at Create Research Programme in Toronto, Canada. He said, “Accumulation of high concentration of glutamate (a type of amino acid) neurotransmitter in the brain is the hallmark of many diseases of the central nervous system. The latest research published in the Journal of Inflammation opens the possibility for stem cells to be used in controlling the machinery of glutamate transport in the context of neuroinflammation.”
Earlier, the therapeutic potential of stem cells from a bunch of sources has been tested in several neurological diseases. Fyyaz Siddiqui itself and with the team’s assistance in their previous studies have demonstrated clearly the capability of stem cells, derived from the first-trimester human umbilical cord, in mitigating the inflammation of CNS and aberrant behaviour in an in vivo model of depression and anxiety.
Not only this but also they have proposed a cellular mechanism that only suggests the stem cells injected systemically as it indirectly affects the signalling pathways in the brain through regulation of the activated immune system at the periphery. As per sources, around a billion people worldwide entailing 1 in 7 teenagers are suffering from some form of mental disorder. Also, according to the pandemic rates, prevalent conditions, such as depression and anxiety went up by more than 25%.
Fyyaz Siddiqui has recommended using stem cells and also he said that his novel finding will definitely provide safe and non-invasive therapeutic options. Also, he talked about this novel finding for targeting inflammation-driven neurotoxic chemical imbalances that are linked to neurological diseases and affective disorders.
This Hyderabad-born scientist studied at Osmania University, Aligarh Muslim University and Western University, Canada. In addition to this, he has also been associated with multiple biotech companies and research institutions in the countries like India, Canada, and the USA. Research says Fyyaz Siddiqui has been inspired by his father Dr MKH Siddiqui, a popular scientist in the field of clay mineralogy. His father is the author of the classic Bleaching Earths published in 1968.
