IgA nephropathy (nuh-FROP-uh-thee), also acknowledged as Berger’s disease, is a kidney syndrome that happens when an antibody called immunoglobulin A (IgA) lodges in your kidneys. This leads to local swelling that, over time, might hamper your kidneys’ aptitude to filter waste, surplus water and electrolytes from your blood. Kidney impairment might be specified by blood and protein in your urine, high blood pressure and inflamed feet. IgA nephropathy generally progresses gradually over many years, but the course of the disease in each individual is indeterminate. Some folks leak blood in their urine without developing problems, some ultimately achieves complete remission and others develop end-stage kidney failure. No cure subsists for IgA nephropathy, but certain medicines can slow its course. Keeping your blood pressure under control and reducing your cholesterol levels also decelerate disease progression.
IgA nephropathy typically doesn’t cause symptoms in the initial stages. The disease can go unobserved for decades and is at times first suspected when routine tests disclose protein and red blood cells in your urine that can’t be seen without a microscope (microscopic hematuria). Signs and symptoms of IgA nephropathy when kidney function is compromised include:
- Cola- or tea-colored urine (instigated by red blood cells in the urine)
- Recurrent episodes of cola- or tea-colored urine, sometimes even observable blood in your urine, generally during or after an upper respiratory or other kind of infection
- Pain in the side(s) of your back below your ribs (flank)
- Froth in the toilet water from protein in your urine
- Inflammation (edema) in your hands and feet
High blood pressure
The conventional treatment for kidney disorders encompasses some oral steroidal medications for an anti-inflammation. In critical circumstances, the patients can be counseled to be on dialysis often. However, this can be taken as only supplementary treatments and to recuperate back the normal kidney function, kidney transplant is the only available option. Moreover, all-time supplementation of steroidal medications can be very detrimental to the body. Thus, medical community had been always in search of some alternative treatment choices to evade steroids and kidney transplantation. Stem cell treatment can be the finest choice for nephrological issues. Stem cells are the naive cells of the body, which can be segregated into many cells upon proper activation. This amazing property of stem cells can be used to treat a multiplicity of medical complications. From the heaps of data, available from numerous clinical trials; it has been witnessed that stem cells once injected into the body, can release some proteins, growth factors and cytokines, to encourage the growth of kidney cells and proximal tubular epithelial cells. Although lots of research is still under way, stem cells can certainly stop the progression of the ailment.