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The Clinical Trials on Stem Cells: Updates and Outcomes in 2023 -24

Clinical Trials

Over the 40 years, the clinical trials on stem cell treatments have been going, heralding promising results and lighting up hope for innovative medical treatments. However, trials are still in the early phases of stem cell therapy and being utilized as an effective alternative treatment method to traditional pharmaceutical based treatments. One notable development involves the usage of mesenchymal stem cells and induced pluripotent stem cells ,which have paved the way for personalized medicine. The main concern with a new treatment option are the long term safety assessments and standardization of outcomes. There are various research papers and journals that focus on these clinical trials that have shown favorable results from initial trials across the globe.

As the approaching months progress, extensive studies and strict medical exams will continue to envision the complete efficiency of stem cell treatments, revolutionizing present-day medicinal drugs and presenting sparkling hope for those struggling.

Here are some resources for you to know more about the clinical trial stage of using stem cells around the world.

 Few Open Stem Cell Trials – Presently, Welcoming New Patients

Completed and Closed Stem Cell Trials with Outcomes

  • Emory University- ALS and MND Stem Cell Clinical Trials
  • Clinical Implementation of mesenchymal stem cells
  • Autologous stem cell transplantation in adult individual having acute lymphoblastic leukemia
  • In vitro differentiation of human placenta-derived multipotent cells into hepatocyte-like cells- Multipotent cells isolated from human term placenta (placenta-derived multipotent cells [PDMCs]) were recognized so that it can differentiate into mesodermal lineage cells, which includes adipocytes and osteoclasts. The low infection rate and younger age of placenta compared with other tissue origins of adult stem cells make these cells appealing target for cell-based therapy.
  • Comparison of human placenta- and bone marrow-derived multipotent mesenchymal stem cells– In this examine, precise production practice-compliant reagents have been utilized to ex vivo enlarge Mesenchymal Stem Cells (MSCs) isolated from human placenta (hpMSC) and human bone marrow (hbmMSC). The objective of the research became to expand a complete comparison between human placenta-derived MSC (hpMSC) and hbmMSC in terms of cellular characteristics, foremost growth conditions, and in vivo protection, so as to determine if hpMSC may want to serve as a viable supply of MSC for clinical trials, considering that placenta is a more conveniently available supply than bone marrow.
  • The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT)– Cellular cardiomyoplasty, a method of transplanting progenitor cells into a place of damaged myocardium, is a capability therapy that could be used to replace or mend necrotic, scarred, or dysfunctional tissue. Desirably, the graft cells must be speedy attainable, effortlessly cultured so that it will guarantee enough for transplantation, and capable of living inside the host myocardium, which commonly presents a difficult environment of low blood glide and immune rejection.
  • Treatment for Peripheral Vascular Disease- Australian Clinical Trials- This trial at the Alfred health center in Melbourne, Australia intends to examine the results of a single injection of the patient’s own peripheral blood stem cells (CD34+) with a placebo injection for treating extreme peripheral arterial disease in twenty subjects. To make certain a dependable outcome, the observation is carried out using a double-blind, randomized safety and feasibility evaluation. Individuals will be kept under observation for facet outcomes, as well as alteration of their medical condition.


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