Detailed Information

DIAGNOSIS with co-morbidity:

– Poor Ovarian Reserve with Premature Ovarian Failure

ALLERGY:

Nil

MEDICAL HISTORY WITH PRESENTING CHIEF COMPLAINT:

A 43yrs/Female came for her complaints of failed IVF since July 1st, 2021. The patient is admitted here for management of her II Infertility with recent concern of failed IVF caused due to Poor Ovarian Reserve with Premature Ovarian Failure (POF). She wants to undergo experimental stem cell therapy to get her POF treated. Prior written consent has been taken before starting the stem cell therapy procedure.

PAST MEDICAL HISTORY:

She has h/o irregular and infrequent menses since 2022 started and she had taken Rx along with a local Gynecologist at her place, which has not helped her to get a successful pregnancy. She has also undergone once for IVF but it was not successful in pregnancy.

OBG HISTORY: G2P2A1L1

– 1st Pregnancy was FTND and normal delivery of female baby.
– No complications before, during & amp; after pregnancy.

FAMILY HISTORY:

NAD

PLAN OF ACTION:

– UC-MSC & amp; Exosomes cellular therapy via intra-ovarian (Bilateral) route
using laparoscopic intervention.
– Stem cells + Exosomes given through the intra-venous route.
– Inj MVI in slow IV infusion of NS.
– Inj Vit C.
– Inj Pan40mg, Inj Monocef1gm & Inj Amikacin BD

OPERATION UNDERTAKEN / PROCEDURE:

1. Stem cells + Exosomes given through intra-venous route.
2. Stem Cell is given into bilateral ovary using laparoscopic intervention route.
3. MVI inj & amp; Inj Vit C was given via slow IV infusion.

IN THE COURSE OF HOSPITAL AND COMPLICATION IF ANY:

The patient was clinically examined and thoroughly investigated, the physician’s opinion taken, and informed written consent taken.
Under GA, Laparoscopically took access to both ovaries and injected in bilateral ovaries about Stem Cells into NS suspension using spinal needles. Cells were inj at multiple sites of both the ovary under the guidance and supervision of Dr. Reena Jain, Gynaecologist, and Laparoscopic Gynaecologist, Dr. Ashta Jain (MD. The patient was given an I/V infusion of Stem Cells + Exosomes given slowly. The procedure went uneventful and post-procedure patient was given Inj. Onden, Inj. Diclofenac, Inj Monocef 1gm & inj. amikacin bd. MVI fluid with other supportive measurements during the hospital stay. Post-procedure was uneventful (no headache or vomiting). At the time of discharge, she is clinically stable and her all vitals are normal.