Autism is an ailment of neural development categorized by diminished social interactions, communication, mood changes, repetitive behavior, metabolic and digestive concerns. Also there is autism spectrum disorder that designates an array of conditions categorized as neuro developmental disorders. Features of these ailments consist of social deficits and communication problems, stereotyped or repetitive behaviors and interests, sensory problems, and in some circumstances, cognitive postponements. These symptoms become apparent usually in the first two years of childhood and affects information processing in the brain by modifying how nerve cells connect and organize. It typically surfaces during the first three years of the kid’s development phase. It decelerates their normal functioning which makes them reliant on others for their most elementary requirements.

Symptoms and causes of autism

Autism cannot actually be outgrown but studies and research have revealed that early intervention can help improve the cognitive capabilities of the kid and help them be more self-regulating and thus improve the quality of life. Incapability to communicate efficiently, trouble in beginning and maintaining relationships, sluggish or diminished speech development, repetitive behavior, over attachment towards materialistic items, reduced human communications, over-sensitivity to loud sounds or uncomfortable when touched, deficiency of attention, hurting themselves, violent behavior toward others and eating non-edible things like chalk, sand, paper, dirt or other such stuffs are some of the common symptoms.

Experts have still not been able to pinpoint the exact reason or situations that result in the development of autism. Numerous studies by experts, scientists, doctors and other researchers have shown some possibilities of the reasons of autism. These are structural or functional mutilation to the brain, mutation of a gene which leads to the abnormal development of the brain which then results in symptoms of autism, prenatal problems such as maternal bleeding in the first trimester of the pregnancy, the existence of me conium in the amniotic fluid, nutrient insufficiency during gestation, environmental aspects such as mercury poisoning, toxins, infections and numerous other factors can be held responsible as the reasons of autism.

Some obvious signs

Given below are some of the signs of autism observed in children:

• The kid is unable to communicate generally. Non-verbal communication and the aptitude to communicate using body language is sternly diminished.
• The kid is inept to establish and maintain peer relationships.
• The youngster is unable to initiate or be a part of normal conversation.
• The child displays signs of slow or compromised spoken language capability.
• The child displays repetitive behavior like rocking, twisting and other obsessive behavior.
• The child is inept to identify or respond to their own names.
• The youngster becomes oversensitive to external stimuli such as loud sound, perky lights, heightened sensory feeling, etc.
• The kid has peculiarly short attention span.
• The kid is likely to self-inflict injuries.
• The child shows violent behavior towards others such as scratching, biting, hair pulling, etc.
• The child displays an obsession with eating unpalatable substances (called as ‘pica’) such as chalk, paint, paper, dirt, etc.

Stem cell treatment for Autism

Although autism is a convoluted and complex neuro-developmental medical condition, numerous specialists have gathered together to reconnoiter the possible reasons of autism and its effects on the brain. There are three substantial indicators that show potentials of being connected with the reasons of autism and they are the deficiency of oxygen supply to the brain, the weakening of the immune system and disproportion of brain activity. The slow functioning of the brain might be accredited to these factors. Researchers and doctors are studying the likelihoods of using regenerative therapy using stem cells as a conceivable treatment for youngsters showing symptoms of autism. The foundation behind this study is that stem cells can regenerate diverse specialized cells from the mother cells and aid to repair the affected neural tissues at the structural, molecular and functional levels. Via this study, specialists are trying to get to the core development of autism with the assistance of paracrine disciplinary functions. This therapy is able to standardize cell differentiation, overhaul the impaired tissue and organs and also yield anti-inflammatory actions.

What improvements can be perceived?

After the accomplishment of the stem cell therapy, patients have shown amazing improvements in numerous aspects such as behavioral, cognitive, sensory and motor doings. Behavioral patterns those were earlier noticeable in kids with autism such as hyperactivity, hypersensitivity, repetitive movements, etc. lessened significantly after the therapy was efficaciously accomplished. Parents of the kids on the spectrum have also reported improvements in attention duration and concentration, eye contact and peer to peer communications.

What is the scientific validation behind using stem cells to treat autism?

Present investigative therapies for autism aim to reverse these aberrations via administrations of antibiotics, anti‐inflammatory agents and hyperbaric oxygen. Regrettably, none of these methodologies address the root causes of oxygen deficiency and intestinal swelling. The validation behind treating autism with umbilical cord tissue-derived mesenchymal stem cells is that autism and its degree of severity has been considerably connected inflammatory and neuro-inflammatory cytokines including macrophage-derived chemokine (MDC) and thymus and activation-regulated chemokine (TARC). Intravenous administration of umbilical cord MSCs has been publicized in multiple clinical trials to decline inflammation. Declining swelling in the autistic patient might assuage symptoms of autism. Via administration of mesenchymal stem cells, we have perceived improvement in patients treated at our facilities.

Stem cells are accountable for the growth of the vital kinds of cells that are required to repair the wear and tear of the body. A kid, affected by autism, is likely to be suffering from neurological impairment. The stem cells aid in treating the impaired brain tissue. The stem cell treatment targets to repair the neural tissue damage at the molecular and cellular level for effectual repair. This has occasioned in the massive improvement of thousands of kids affected by autism all across the globe. It is imperative to approach only the reputable hospitals for getting the best stem cell treatment for autism. The specialists in such hospitals follow a well-thought-out methodology.