Osteoarthritis is a chronic condition of joints where the lining cartilage gets exhausted. When medications and workout didn’t work, doctors,up till now,recommended joint replacement. Joint replacements are generally implemented when the joint is totally worn out. However, there are a lot of publics with mild and moderate osteoarthritis. Such individuals stand to profit from cell based biological treatments after appropriate assessment. This will delay the necessity for a joint replacement.
Elements responsible for osteoarthritis
Although scientists have quoted osteoarthritis as an autoimmune disorder, there are some other common risk elements that can exacerbate the condition such as:
- Being obese
- Joint injury
- Joint imperfections
- Hereditary abnormality
- Joints being over stressed because of some jobs such as sports, knee bending, repetitive motions
- Pregnancy related calcium loss in case of females, oestrogen shortage, etc.
- Existence of c reactive proteins in urine
- High bone solidity
Bone deficiencies are one of the most serious complications patients and physicians are encountering and the leading spur for new research concentrating on the requisite for new tissue regeneration therapies. Studies on mesenchymal stem cells are transforming the way we treat bone sicknesses,sloping the shift away from surgery.
Mesenchymal stem cells in joint disease and repair
Doctors note that mesenchymal stem cells are identified to have a potential for articular cartilage regeneration, however this favorable research is fixated on surgical transplant of the stem cells. Now doctors have found that for the treatment of sweeping cartilage loss in osteoarthritis, a substitute delivery approach would be more appropriateand that is injection therapy. The inoculation of mesenchymal stem cells has produced encouraging outcomes in pre clinical models of joint disease.
What is stem cell therapy?
Stem cells are taken from the patient. Mesenchymal stem cells are found in the bone marrow, fat and perhaps in other tissues and are accountable for rebuilding and regenerating the body. These stem cells aid the body to renovate and heal itself. Mesenchymal stem cells are also able to segregate into ligaments, tendons and cartilage, and maintain a distinct role in the non-surgical treatment of osteoarthritis, management of chronic pain and sports wounds. What is so promising is that that stem cells might have the potential to avert a knee, hip, shoulder or ankle replacement or fusion, repair a torn rotator cuff or labrum and heal a meniscus tear of the knee. Our body holds the power of repair in the stem cell, but it often needs to be focused in a zone of injury or chronic degeneration to be truthfully effective. Symptoms related with the following conditions possibly treated by stem cell shots for osteoarthritis:
- Rotator cuff tendonitis
- Biceps tendonitis
- Osteochondral defects
- Non-healing fractures
- Labral tears of the hip and shoulder
- Chronic epicondylitis (tennis and golfer’s elbow)
- Ligament injuries
- Degenerative disc disease
- Chronic neck and back pain
- Post-concussion syndrome
- Chronic groin and hamstring strains
- avascular necrosis of the hip
Stem cell therapy is implemented by taking out stem cells from the body, sanitizing them and then inoculating them back into the impaired region. The stem cells cannot work alone and they necessitate assistance from growth and support factors found in other tissues and blood. We follow stringent FDA guidelines in the usage of stem cells and at no time do we manipulate, expand or cultivate stem cells in culture. We believe the finest stem cell therapies are derived from the patient in high concentration, and positioned back into the zone of treatment. Manipulation and imitation of stem cells in culture might incapacitate these cells and might also result in the development of mutation that could result in cancer. The usage of the patient’s own adult stem cells avoids this problem. The region of injury or arthritis is treated with both stem cells and platelet rich plasma (PRP). If stem cells are the seeds in the grassland, PRP is the fertilizer that supports the grassland to grow. PRP, an amalgamation of growth factors and platelets naturally found in the body, offers cell signals and nourishment to aid the stem cells to flourish and develop into new joints, tendons, ligaments and other body portions. PRP not only elicits stem cell development, but can also help stem cells regenerate on their own inside the body, and can also entice circulating stem cells to the region of injury. We have employed PRP alone in the treatment of several injuries and pain complications.
Maximum cases of stem cell and PRP treatments are efficacious, and circumvent the pain, infirmity, down time and the risksrelated with major surgery. There is trifling retrieval from a stem cell or PRP treatment, generally refereed by tenderness in the area that was treated and there is also a risk of bruising. There have been nilrumors of serious adverse effects in the scientific works when adult mesenchymal stem cells are used in these processes. Subsequently, the patient is fortified to use the joint normally and follow-up treatments of PRP are administered in once-a-month intervals to continue to permit the stem cells to do their job. Since stem cell treatment is very benign, it can be repeated in the joint if essential to obtain optimum outcomes. Also, having treatment with stem cells would not make an individual unqualified for surgery.
How long will it take to see results?
Since each ailment and patient is unique, there is no assurance of what outcomes will be attained or how rapidly they might be observed. As per patient feedback, several patients report outcomes in one to three months; however, it might take as long as six to nine months. Individuals keen on stem cell therapy are urged to refer with their doctor before selecting investigational autologous adipose-derived stem cell therapy as a treatment alternative.